Associate Scientist II, CNS
- Alnylam Pharmaceuticals, Inc.
- Cambridge, Massachusetts
- Full Time
Contribute to the design and execution of studies to characterize molecules for RNAi therapeutic programs, including rodent disease models. Develop and conduct assays such as qPCR, western blot, ELISA, that support in vivo studies. Conduct in vivo procedures in both rats and mice, including therapeutic administration using established methodologies. Analyze, report, and present scientific data in group meetings. Prepare clearly articulated experimental reports and data presentations. Prepare of SOPs/protocols. Track samples in databases including but not limited to Electronic Laboratory Notebook (ELN), Laboratory Information Management System (LIMS), Smart Refrigeration systems, Smartsheet's and other proprietary databases. Adapt quickly to changing priorities in a dynamic work environment. Communicate openly and directly with lab groups to provide sufficient solutions that will work for all team members. Minimum B.S. degree in a life sciences-related discipline such as Molecular Biology, Cell Biology, or Genetics Basic rodent in vivo skills (animal handling, subcutaneous/intravenous dosing, blood collection, and necropsy/tissue dissection expertise). The ability to collect peripheral tissues, dorsal root ganglia (DGRs), and brain regions is highly desirable. Demonstrate keen knowledge of experimental design, underlying scientific principles, and the ability to rigorously and independently analyze results, propose future directions, and generate clear reports Must be flexible, open to new tasks and challenges and able to work on tight deadlines. Exceptional interpersonal skills and the ability to function at a high capacity within a fast-paced team environment. Excellent attention to detail, organizational skills, eagerness to learn, and the ability to follow written and verbal instruction. Working knowledge of standard Microsoft Office applications including Excel, GraphPAD, Outlook, PowerPoint, and Word. Familiarity with laboratory automation and liquid handling systems is a plus.