Research Engineer II

Site: The Brigham and Women's Hospital, Inc.

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

Summary

Will support the development of systems and probes being developed for research and clinical applications through all development phases, including design, prototyping, fabrication, validation, utilization, and maintenance. Highly desired qualities are creativity, attention to detail, and experience with biomedical optics. Will participate on multiple projects, and assist in the design and fabrication of , mechanical, and electronic components in new devices, reviewing and documenting the manufacturing process for in-production devices, and troubleshooting the performance of existing systems.

Does this position require Patient Care?

No

Essential Functions

• Design new, mechanical, and electronic components and systems using industry standard design control processes.
• Develop complex mechanical systems.
• Design, fabricate, and validate mechanical enclosures, mounts, and subassemblies.
• Design and implement vibration, thermal, and environmental testing methods.
• Produce prototypes of new optical, mechanical, and electronic components and systems.
• Document new and existing parts and procedures to facilitate manufacturing.
• Validate the conformance of components and systems to specifications.
• Troubleshoot and take corrective action for components and systems not meeting specifications.

Qualifications

Education

Bachelor's Degree Related Field of Study required

Can this role accept experience in lieu of a degree?

No

Licenses and Credentials

Experience

Experience in device engineering in a hospital, industry, or academic 1-2 years preferred and Experience in medical engineering 0-1 year preferred

Knowledge, Skills and Abilities

• Skill in management of engineering projects and/or personnel.
• Ability to work in an interdisciplinary team of scientist, engineers and medical doctors.
• Ability to diagnose and solve technical and/or system problems of moderate complexity.
• Computer literacy to the level of at least word processing, spreadsheets, databases, graphics, statistics, engineering tools and programming.
• Skill in technical writing.
• Experience using fabrication tools.

Additional Job Details (if applicable)

Physical Requirements

• Standing Constantly (67-100%)
• Walking Constantly (67-100%)
• Sitting Rarely (Less than 2%)
• Lifting Frequently (34-66%) 35lbs+ (w/assisted device)
• Carrying Frequently (34-66%) 35lbs+ (w/assisted device)
• Pushing Frequently (34-66%)
• Pulling Frequently (34-66%)
• Climbing Occasionally (3-33%)
• Balancing Constantly (67-100%)
• Stooping Occasionally (3-33%)
• Kneeling Occasionally (3-33%)
• Crouching Occasionally (3-33%)
• Crawling Occasionally (3-33%)
• Reaching Frequently (34-66%)
• Gross Manipulation (Handling) Constantly (67-100%)
• Fine Manipulation (Fingering) Frequently (34-66%)
• Feeling Constantly (67-100%)
• Foot Use Rarely (Less than 2%)
• Vision - Far Constantly (67-100%)
• Vision - Near Constantly (67-100%)
• Talking Constantly (67-100%)
• Hearing Constantly (67-100%)

Description:

We are seeking a Research Engineer II, in the Traverso Lab at Brigham and Women's Hospital with a background in analytical chemistry. Our research group consists of an interdisciplinary team of engineers, chemists, biologists, pharmaceutical scientists, and physicians focused on developing clinically translatable biomedical devices and drug delivery systems.

The Research Engineer (analytical scientist) will be a member of the bioanalytics team with the following responsibilities:

• Operate LCMS, ELISA, PCR, GCMS, and ICP-MS equipment to analyze pre- clinical samples provided by formulation teams.
• Prepare pre-clinical LCMS and GCMS samples with high precision and quality.
• Develop bioanalytical methods for the detection of target molecules in complex matrices (plasma, serum, organ tissues, urine, etc).
• Design automated liquid handling programs for bioanalytical sample preparation, including: protein precipitation, solid phase extraction (SPE), and supported liquid extraction (SLE).
• Validate bioanalytical methods and evaluate the validation results against internal guidelines.
• Troubleshoot and repair analytical instrumentation, and/or coordinate onsite repair from OEM service provider.
• Write and prepare standard operating procedures.
• Support lead analytical chemists with requests, as needed.
• Manage sample tracking in LIMS.
• Document daily tasks and upload files to ELN.

Job Requirements:

B.S. (M.S. preferred) in a relevant scientific field (i.e. chemistry, biology, biochemistry, chemical engineering); at least two years' specialized experience (which may include experience gained as an undergraduate) with analytical chemistry; chromatography and mass spectrometry experience; experience working with and maintaining technical instruments/equipment; ability to multitask and organize multiple experiments and work assignments simultaneously and work both independently and as part of a team; strong time management, communication, and problem-solving skills; and awareness of basic

safety issues and ability to follow safety procedures and maintain a safe work

environment.

Candidate must have experience with chromatographic and mass spec instrumentation with prior experience in complex bioanalytical sample preparation. Familiarization with chemstation, OpenLab, Masshunter, and Analyst is a plus, and prior experience operating Agilent instrumentation is preferred. Individual must have basic mechanical capabilities and very strong independent problem solving capabilities.

Candidate must have self-motivation and willingness to learn new tools and techniques; strong organizational, interpersonal, and communication skills; ability to work independently and as part of a team; comfort summarizing and reporting results to interdisciplinary researchers; commitment to exceeding standards and producing accurate, high quality work; meticulous attention to detail; practiced documentation skills; and ability to follow safety procedures and maintain a safe work environment.

Remote Type

Onsite

Work Location

65 Landsdowne Street

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$49,504.00 - $72,404.80/Annual

Grade

6

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at ....

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.