Process Development Chemist

Job Summary:

The Development Chemist I supports peptide manufacturing by executing chemical synthesis, purification, and drying processes under established procedures and occasional supervision. This role involves monitoring reactions, preparing solutions, operating HPLC systems, and performing in-process checks to ensure product quality. The chemist also maintains strict safety and cleanliness standards while assisting with troubleshooting and reporting equipment issues as needed. This role contributes directly to PolyPeptide's commitment to delivering exceptional quality and on-time delivery to our customers.

Key Responsibilities:

• Checks reactor system for proper operation in accordance with SOP and/or operation manual.
• Under occasional and necessary supervision and direction, measures and mixes ingredients according to the BPR (Batch Production Record).
• During processing, monitors chemical reactions (color and completeness of chemical reactions) and under occasional and necessary direction of supervision responds with appropriate actions to ensure proper processing.
• Using established procedures (safety and process) and under occasional and necessary supervision, performs intermediate chemical processing steps.
• Prepares solutions for purification.
• Under occasional supervision, purifies crude peptide by using HPLC's.
• Conducts lyophilization process according established guidelines.
• Performs drying processes in accordance with established processes and procedures.
• Performs in-process checking of the fractions by using analytical HPLC and reports results to supervision and/or Sr. Development Chemist personnel.
• Makes basic "Go - No Go" processing decisions.
• Reports any significant problems or issues regarding equipment used in processing to supervision. May perform basic and/or general machine/equipment troubleshooting.
• Is responsible for maintaining high safety, housekeeping and cleanliness standards.
• Performs any and all additional duties as required for this position.

Qualifications:

Education & Experience

• Required Education:
• Bachelor's degree in chemistry or chemical engineering
• Experience:
• 2+ years of professional experience in pharmaceutical/biotechnology laboratory.

Skills & Competencies

• Technical Skills:
• Proficiency in HPLC systems,
• cGMP processes
• Soft Skills:
• Proficient use of Microsoft Office suite of applications (Outlook, Excel, Word, PowerPoint, Teams, etc.)
• Ability to work as part of a team and also independently with minimal to no supervision
• Ability to rapidly change focus during times of shifting or changing priorities
• Impeccable technical writing skills with extreme attention to detail, specifically the lexicology and grammatology of written English text as applied to technical writing
• Excellent organizational, multitasking, and communication skills
• Competencies:
• Chemical Process Execution and Monitoring
• Proficiency in HPLC and Peptide Purification Techniques
• cGMP Compliance and Documentation Accuracy
• Attention to Detail and Technical Writing
• Adaptability and Team Collaboration

Work Environment & Physical Demands:

This role may be based in an office, laboratory, or GMP manufacturing environment, depending on the position. Office-based employees primarily work at a computer in a standard office setting, while lab and manufacturing roles may require work in controlled environments with appropriate gowning and PPE.

Physical demands may include:

• Prolonged sitting or standing, depending on the role.
• Frequent movement between work areas and occasional lifting of up to 25 pounds.
• Performing repetitive tasks, including pipetting, weighing, and data entry.
• Use of hands for data entry, equipment operation, or laboratory tasks.
• Exposure to chemicals, equipment noise, or temperature-controlled environments in lab or production settings.
• Occasional evening, weekend, or overtime hours to meet production or testing deadlines.
• Reasonable accommodations will be made as needed.

Salary: $65k-$85k per year

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.