Senior Scientist, Delivery Sciences (Immunology)

  • Alnylam Pharmaceuticals, Inc.
  • Cambridge, Massachusetts
  • Full Time

Develop and lead advanced in vitro and ex vivo immune assay platforms. Develop and optimize in vivo immune-related murine disease models. Integrate and interpret multi-parametric flow cytometry data. Collaborate with platform teams, early development groups, and external CROs to support cross-functional research objectives. Present scientific findings at internal governance meetings, contribute to external publications, and support IND-enabling research. Ph.D. in Immunology, Cell Biology, or a related discipline, with a focus on immune-related disease mechanisms. A total of 3-6 years of relevant experience in translational immunology and cell biology, including academic postdoctoral training and preferably 2+ years of industry experience. Strong expertise in adaptive immunology, murine disease models, and immune-mediated tissue damage. Strong publication record in peer-reviewed journals in cell biology, immunology, or translational research. Primary immune cell culture Flow cytometry (high-parameter analysis, cell sorting) Biomarker assays (ELISA, MSD, cytokine profiling) qPCR, IHC, scRNA-seq, and bioinformatics pipelines (R, IPA) Direct experience with oligonucleotide-based therapeutics is a plus. Demonstrated ability to independently design, execute, and interpret complex biological experiment. Excellent communication, collaboration, and interpersonal skills, with the ability to present data clearly and effectively in both written and oral formats, and to work productively across multidisciplinary teams.

Job ID: 489204855
Originally Posted on: 8/13/2025

Want to find more Chemistry opportunities?

Check out the 15,901 verified Chemistry jobs on iHireChemists