Scientist, Discovery Biotherapeutics, Antibody Drug Conjugate Technologies

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:careers.bms.com/working-with-us .Working With UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .Scientist, Discovery Biotherapeutics, Antibody Drug Conjugate TechnologiesSummaryThe Discovery Biotherapeutics team is dedicated to the discovery and advancement of novel biotherapeutic candidates, leveraging cutting-edge science and innovative technologies to drive the drug discovery pipeline. We seek to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates, and endogenous proteins in order to optimize their utility as therapeutic agents. Our team collaborates across disciplines to advance biologic programs in Oncology, Immunology, Cardiovascular, and Neuroscience with the ultimate goal of bringing new groundbreaking therapies to patients. The Protein Conjugation team leads the strategy and execution in generating a dynamic range of protein conjugates for our therapeutic pipeline, including oligos, small molecules, and peptides. We are looking for a collaborative, highly motivated scientist with expertise in antibody drug conjugates (ADC) technologies. The candidate should have a deep understanding and experience with antibody drug conjugation methods. The candidate is expected to have strong collaborative skills to ensure robust partnerships with biologists, antibody discovery and engineering & bioanalytical scientists to advance ADC projects.Position Responsibilities:The role will involve carrying out laboratory experiments related to ADC conjugation, associated purification and analytical characterization of the conjugatesDesign, produce, and characterize antibody-drug conjugates (ADCs) with a high degree of independence, on a variety of scales, and in alignment with product development guidelines and QC criteriaCollaborate with a diverse team of biologists and chemists to answer scientific questions and drive forward new conjugation platformsPresent own work within and outside their immediate team, with the opportunity to represent the team in cross-functional programs and initiativesThe candidate will encourage ideas for continuous improvement activities & new technology development initiativesContribute to patents, publications, and technical reports.Basic Qualifications:Bachelor's Degree5+ years of academic and / or industry experienceOrMaster's Degree3+ years of academic and / or industry experienceOrPh.D. or equivalent advanced degree in the Life SciencesNo experience necessaryPreferred Qualifications:Proficiency in bioconjugation chemistries (lysine, inter-chain cysteine and/or site-specific cysteine and other) is requiredExperience in purification strategies using various chromatographic techniques such as affinity, size exclusion, ion-exchange, hydrophobic interaction, and tangential flow filtration (TFF)Demonstrated experience in analytical characterization of ADCs including SEC, RP-HPLC, LC-MS, CE-SDS, ELISA, DSC, and HICExperience in analytical method development and with chromatography and MS data analysis platformsExperience with biological assays, including flow-based assays, and measuring cytotoxic activity for ADC characterization, would be highly desirableDemonstrated record of scientific accomplishments and publicationsExcellent organizational, interpersonal, and communication skillsDemonstrated ability to work effectively within a team environmentIf you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.The starting compensation for this job is a range from $128,420 - $155,600, plus incentive cash and stock opportunities (based on eligibility).The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Careers Site .Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as "Transforming patients' lives through sciencea ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promotingglobal participationin clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplaceaccommodations/adjustmentsand ongoing support in their roles. Applicants can request a reasonable workplaceaccommodation/adjustmentprior to accepting a job offer. If you require reasonableaccommodations/adjustmentsin completing this application, or in any part of the recruitment process, direct your inquiries ******. Visitcareers.bms.com/eeo-accessibilityto access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:/Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.