Scientist

The scientist will be a member of a team providing support for the early-stage pipeline of small molecule (SM) and protein therapeutics.

location: South San Francisco, California
job type: Contract
salary: $40.00 - 46.69 per hour
work hours: 9 to 5
education: Bachelors

responsibilities:

• Characterize small molecule (SM)-protein and protein-protein interactions using Surface Plasmon Resonance (SPR) and Bio-Layer Interferometry (BLI) technologies.
• Perform assay development, hit characterization, and hit ranking for interaction studies.
• Design and execute kinetic and affinity binding assays using SPR instruments (e.g., Cytiva/Biacore) and BLI instruments (e.g., Sartorius Octet, GatorBio).
• Utilize additional biophysical techniques, such as:
  
  
  • nanoDSF (Differential Scanning Fluorimetry): to assess protein stability.
  • TRIC (Temperature-Related Intensity Change) / spectral shift assays: to analyze biomolecular interactions.
• Operate liquid handling automation platforms, including:
  
  
  • Bravo platform: for high-throughput liquid handling.
  • ECHO acoustic dispenser: for contactless and precise sample transfer.
• Independently plan and execute scientific experiments, including defining project timelines, milestones, methodologies, and resource requirements.
• Analyze and interpret scientific data; regularly document and communicate experimental progress and results.
• Collaborate cross-functionally with other scientists and teams to advance research objectives.
• Stay up to date with current developments in biophysics, protein interaction analysis, and relevant technologies through literature and conferences.
• Provide subject-matter expertise to supervisors and colleagues; participate in scientific meetings at the national and international level.
• Contribute to publications, patent applications, and regulatory submissions by delivering high-quality scientific results.
• Mentor and support research associates and laboratory assistants in scientific and technical tasks.

qualifications:

• A focus on kinetics and binding affinity characterization with experience using Carterra Biacore SPR and/or Sartorius BLI instruments.
• Proven track record of academic accomplishments (i.e., peer-reviewed publications and/or patents)
• Demonstration of good lab practices, with particular attention to safety
• Clear understanding of binding experiments as well as a general knowledge of related methods and data fitting computer applications.
• Attendance to one of David Myszkas label free workshops.
• Excellent communication skills (both written and oral)

#LI-CV1

skills: GLP (Good Laboratory Practice)

Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact ....

Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).

This posting is open for thirty (30) days.

Qualified applicants in San Francisco with criminal histories will be considered for employment in accordance with the San Francisco Fair Chance Ordinance.

Qualified applicants in the unincorporated areas of Los Angeles County with criminal histories will be considered for employment in accordance with the Los Angeles County's Fair Chance Ordinance for Employers.

We will consider for employment all qualified Applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance.