Postdoctoral Scholar - Clinical Translational Scientist

About Us
Our team is dedicated to the development of advanced, non-invasive diagnostics to inform the care of patients with cancer and other diseases. We care deeply about creating a place where folks can do their best work from the start. This means enjoying camaraderie and challenges as a team. This means solving hard problems and troubleshooting together. Our ideal teammate thrives when working side by side with crossfunctional colleagues. Our company was founded in 2021, backed by 5AM Ventures through its 4:59 Initiative incubator engine. We are based in the vibrant Seaport district of Boston.
The Role
This is a newly established role in close collaboration with Dana-Farber Cancer Institute (DFCI), designed to accelerate our efforts in understanding and overcoming therapeutic resistance in breast and gynecologic cancers. This position offers a unique opportunity to work at the intersection of academic rigor and translational application, embedded within a dynamic biotech environment and supported by DFCIs clinical and scientific excellence. As a Postdoctoral Scholar, youll be encouraged to lead independent research projects that result in high-impact publications and shape future diagnostic approaches. You will be embedded within our translational science team and work cross-functionally across research, computational biology and external collaborations. The postdoc will be encouraged to lead independent projects resulting in high impact publications, present at conferences and prepare for long-term careers in academia or industry. Responsibilities

• As a subject matter expert within breast and gynecological cancers, you will play a key role with our translational science department to provide scientific, clinical, strategic, and operational input in mechanisms of resistance to PARP inhibitors.
• Well depend on you to dig into the science of current and future indications and conduct diligence to understand the landscape for diagnostics and biomarkers.
• Work closely with external experts, and investigators to accumulate scientific and medical knowledge necessary to support clinical development plans and study designs and protocols
• Collaborate with cross-functional teams, including the product development and external research teams to ensure successful study execution
• Develop and maintain relationships with key opinion leaders, investigators, and advisors
• Analyze and interpret clinical data using appropriate statistical methods and communicate results to internal and external stakeholders
• Prepare and present clinical study reports, scientific presentations, and publications
• Ensure that all clinical research activities are conducted in compliance with ethical, regulatory, and company policies
• Stay up-to-date with the latest developments in clinical research, regulatory requirements, and the therapeutic landscape in areas of interest to the company
• Participate in the review and interpretation of preclinical and clinical data
• Provide scientific and clinical input into regulatory submissions, including clinical study reports, briefing documents, and responses to regulatory queries

Requirements

• PhD or equivalent degree in breast and/or gynecological cancer biology, epigenetics/epigenomics, or related field
• Strong knowledge of clinical research design, statistical methods, and regulatory requirements
• Strong analytical and problem-solving skills, with attention to detail
• Clear and open communication skills, and experience communicating across cross functional partners

The minimum base salary for this position is $72,000. Compensation is based on the number of months of relevant postdoctoral experience the successful candidate brings to the role. Please note that the base salary is fixed and not subject to negotiation. We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.