Sr. Scientist I/II Analytical Method Development
- Ashvattha Therapeutics
- Redwood City, California
- Full Time
Sr. Scientist I/II - Analytical Method Development
Redwood City, CA
Type: Full-time
Min. Experience: Some Experience
Salary: $120,000 - $160,000
Ashvattha Therapeutics, a clinical stage biopharmaceutical company located in Redwood City, is seeking a motivated Senior Scientist, Analytical Method Development. Ashvattha Therapeutics is focused on developing novel nanomedicines, HD therapeutics (HDTs), to treat unmet medical needs in ophthalmology, neurology, inflammatory diseases, and neuro-oncology. Our HD platform builds therapeutics that are selectively taken up only by inflamed tissues, allowing us to treat diseases with unprecedented precision.
This position reports to the Director, Analytical Research and Development and will develop analytical methods and test various drug substances and drug products to support Medicinal Chemistry, Translational, Manufacturing, and CDMOs. The successful candidate will be part of a dynamic, interdisciplinary team and require a high degree of creativity and initiative. This is an exciting opportunity to help drive the development of novel therapies for unmet medical needs in multiple indications.
The Position
The Sr. Scientist will serve as a key member of our development team, working on-site full-time, in our Redwood City laboratory, focusing on novel early and late-phase programs.
Duties and Responsibilities - Essential Functions
Develop various analytical methods.
Test various drug substance/drug product samples.
Manage, set up, and maintain all instruments in the analytical lab.
Keep and accurately maintain detailed electronic laboratory notebooks.
Design stability studies, prepare protocols, and monitor ongoing stability studies in-house and at various CDMOs
Perform tasks per protocols as required.
Additional responsibilities may be added as required.
Job Requirements
Ph.D. degree in Chemistry, Analytical Chemistry, or closely related scientific area is required along with a minimum of 5 years of pharmaceutical industry experience.
In-depth expertise with analytical method development and validation with HPLC, UPLC, and SEC-MALS
Expertise in HPLC, HPLC/UPLC, LC-MS, ICP-MS, SEC-MALS and NMR analytical techniques is preferred.
Prior experience with analytical method development and validation for small molecule drugs.
Experience with analytical method development and various tests for polymer-drug conjugates and/or biologics drug candidates are required.
Experience with injectable and oral dosage forms
Independent, problem-solving, and troubleshooting skills.
Technical writing experience such as protocols, reports, SOPs, and preparing CMC sections of IND.
Knowledge of GLP & GMP requirements
Well organized and self-directed
Ability to communicate scientific findings and recommendations in one-on-one discussions, departmental meetings, and prepare reports.
Ability to work in a fast-paced, dynamic environment with multiple projects and priorities.
Must be able to work on site at our Redwood City facility, five days per week.
About Ashvattha
This is a unique opportunity to join a team focused on the development of a new class of precision medicines that selectively treat diseased cells in regions of inflammation. By making precision medicine even more precise, our nanomedicine technology has the potential to change the standard of care across ophthalmology, neurology, inflammatory diseases and neuro-oncology. You will have the opportunity to learn new skills and gain a better understanding of cutting-edge technology.
We have a comprehensive compensation package including fully paid medical, dental and vision benefits for you and your family. We want our employees to become shareholders and offer new hire stock options. The company also offers participation in the annual bonus program. The salary range (not including bonus) for PhD candidates located in the Bay Area with 5-8 years of directly related work experience is $130,000 - $153,000, PhD candidates with 8+ years of experience can expect to make between $140,000 - $165,000, depending on years of experience and relevant skill sets.
Must be able to work on-site at our Redwood City Laboratory
Redwood City, CA
Type: Full-time
Min. Experience: Some Experience
Salary: $120,000 - $160,000
Ashvattha Therapeutics, a clinical stage biopharmaceutical company located in Redwood City, is seeking a motivated Senior Scientist, Analytical Method Development. Ashvattha Therapeutics is focused on developing novel nanomedicines, HD therapeutics (HDTs), to treat unmet medical needs in ophthalmology, neurology, inflammatory diseases, and neuro-oncology. Our HD platform builds therapeutics that are selectively taken up only by inflamed tissues, allowing us to treat diseases with unprecedented precision.
This position reports to the Director, Analytical Research and Development and will develop analytical methods and test various drug substances and drug products to support Medicinal Chemistry, Translational, Manufacturing, and CDMOs. The successful candidate will be part of a dynamic, interdisciplinary team and require a high degree of creativity and initiative. This is an exciting opportunity to help drive the development of novel therapies for unmet medical needs in multiple indications.
The Position
The Sr. Scientist will serve as a key member of our development team, working on-site full-time, in our Redwood City laboratory, focusing on novel early and late-phase programs.
Duties and Responsibilities - Essential Functions
Develop various analytical methods.
Test various drug substance/drug product samples.
Manage, set up, and maintain all instruments in the analytical lab.
Keep and accurately maintain detailed electronic laboratory notebooks.
Design stability studies, prepare protocols, and monitor ongoing stability studies in-house and at various CDMOs
Perform tasks per protocols as required.
Additional responsibilities may be added as required.
Job Requirements
Ph.D. degree in Chemistry, Analytical Chemistry, or closely related scientific area is required along with a minimum of 5 years of pharmaceutical industry experience.
In-depth expertise with analytical method development and validation with HPLC, UPLC, and SEC-MALS
Expertise in HPLC, HPLC/UPLC, LC-MS, ICP-MS, SEC-MALS and NMR analytical techniques is preferred.
Prior experience with analytical method development and validation for small molecule drugs.
Experience with analytical method development and various tests for polymer-drug conjugates and/or biologics drug candidates are required.
Experience with injectable and oral dosage forms
Independent, problem-solving, and troubleshooting skills.
Technical writing experience such as protocols, reports, SOPs, and preparing CMC sections of IND.
Knowledge of GLP & GMP requirements
Well organized and self-directed
Ability to communicate scientific findings and recommendations in one-on-one discussions, departmental meetings, and prepare reports.
Ability to work in a fast-paced, dynamic environment with multiple projects and priorities.
Must be able to work on site at our Redwood City facility, five days per week.
About Ashvattha
This is a unique opportunity to join a team focused on the development of a new class of precision medicines that selectively treat diseased cells in regions of inflammation. By making precision medicine even more precise, our nanomedicine technology has the potential to change the standard of care across ophthalmology, neurology, inflammatory diseases and neuro-oncology. You will have the opportunity to learn new skills and gain a better understanding of cutting-edge technology.
We have a comprehensive compensation package including fully paid medical, dental and vision benefits for you and your family. We want our employees to become shareholders and offer new hire stock options. The company also offers participation in the annual bonus program. The salary range (not including bonus) for PhD candidates located in the Bay Area with 5-8 years of directly related work experience is $130,000 - $153,000, PhD candidates with 8+ years of experience can expect to make between $140,000 - $165,000, depending on years of experience and relevant skill sets.
Must be able to work on-site at our Redwood City Laboratory
Job ID: 487056039
Originally Posted on: 7/27/2025
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