Scientist, Process Development

At Gilead, were creating a healthier world for all people. For more than 35 years, weve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the worlds biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gileads team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and were looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

We're looking for a highly motivated scientist to join our Process Chemistry Department and make a significant impact within the Materials Sciences & Engineering group. This dynamic role requires a blend of hands-on scientific expertise and collaborative leadership, frequently partnering with diverse teams such as medicinal chemistry and formulation. Your core responsibilities will center on material-related subjects, including solid-state chemistry, crystallization & scale-up, particle engineering, and process optimization.

Responsibilities:

• Lead Solid Form Strategy: Collaborate closely with process chemists, analytical chemists, and formulation scientists to screen, characterize, identify, and select optimal API/intermediate solid forms for development.
• Design & Optimize Isolation Processes: Conduct thorough research to design, develop, and scale up API crystallization and isolation processes, ensuring the drug substance meets target material profiles (purity, polymorph, stability, and particle characteristics).
• Drive Advancement of Development Programs: Provide crucial materials and engineering expertise to accelerate API development programs. You'll critically evaluate processes for efficiency, scalability, safety, and robustness, preparing programs for successful technical transfer and commercialization.
• Resolve Complex Challenges: Partner with scientists across functional areas to address development challenges. Analyze complex problems and assess data with ingenuity and creativity to develop innovative solutions. Think critically and independently, suggesting suitable development strategies and applying necessary resources for problem resolution.
• Provide Scientific Guidance: Advise project teams on the initiation, planning, and execution of laboratory experimentation related to material and engineering topics.
• Disseminate Scientific Findings: Clearly present and interpret research data and conclusions. Summarize key scientific findings in comprehensive reports to support patent applications and regulatory filings, and contribute to the scientific community through peer-reviewed publications and conference presentations.
• Foster Innovation & Capability Growth: Champion the adaptation of new technologies (e.g., predictive tools) to advance development and enhance organizational capabilities. Demonstrate technical proficiency, scientific creativity, and independent thought in proposing experimental design and strategy, fostering a collaborative problem-solving spirit.
• Lead Solid Form Strategy: Collaborate closely with process chemists, analytical chemists, and formulation scientists to screen, characterize, identify, and select optimal API/intermediate solid forms for development.
• Design & Optimize Isolation Processes: Conduct thorough research to design, develop, and scale up API crystallization and isolation processes, ensuring the drug substance meets target material profiles (purity, polymorph, stability, and particle characteristics).
• Drive Advancement of Development Programs: Provide crucial materials and engineering expertise to accelerate API development programs. You'll critically evaluate processes for efficiency, scalability, safety, and robustness, preparing programs for successful technical transfer and commercialization.
• Resolve Complex Challenges: Partner with scientists across functional areas to address development challenges. Analyze complex problems and assess data with ingenuity and creativity to develop innovative solutions. Think critically and independently, suggesting suitable development strategies and applying necessary resources for problem resolution.
• Provide Scientific Guidance: Advise project teams on the initiation, planning, and execution of laboratory experimentation related to material and engineering topics.
• Disseminate Scientific Findings: Clearly present and interpret research data and conclusions. Summarize key scientific findings in comprehensive reports to support patent applications and regulatory filings, and contribute to the scientific community through peer-reviewed publications and conference presentations.
• Foster Innovation & Capability Growth: Champion the adaptation of new technologies (e.g., predictive tools) to advance development and enhance organizational capabilities. Demonstrate technical proficiency, scientific creativity, and independent thought in proposing experimental design and strategy, fostering a collaborative problem-solving spirit.

Basic Qualifications:

• Doctorate OR
• Masters and 4+ years of relevant experience OR
• Bachelors and 6+ years of relevant experience

Preferred Qualifications:

• Fundamental understanding of physical chemistry topics, including but not limited to thermodynamics, reaction & crystallization kinetics, and polymorphism.
• Experience with solid form screening (including salt and co-crystal evaluation and selection).
• Proficiency in solid form characterization techniques such as X-ray diffraction, thermal analysis, microscopy, and spectroscopic methods (e.g., Nuclear Magnetic Resonance (NMR), Infrared, and Raman spectroscopy).
• Experience in developing, modeling, and scaling up particle engineering and isolation processes (e.g., crystallization, filtration, drying, wet/dry milling).
• Familiarity with process modeling using commercial tools (e.g., DynoChem, Computational Fluid Dynamics (CFD) simulation) and computational solid-state chemistry.

The salary range for this position is: $146,540.00 - $189,640.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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