Research Associate II - Type 1 Diabetes Research

  • City of Hope
  • Duarte, California
  • Full Time

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

A Research Associate II position is available in the laboratory of Dr. Melanie Shapiro, PhD, in the AR-DMRI Department of Diabetes Immunology. You will perform a variety of experiments related to the genetics and immunology of type 1 diabetes.

The Shapiro laboratory currently studies germline genetic variants predicting response to immunotherapies for type 1 diabetes as well as somatic variants in the pancreas and immune cells of organ donors with type 1 diabetes.

For more information on the Shapiro Laboratory please visit here:

For more information on the Arthur Riggs Diabetes & Metabolism Research Institute please visit here:

As a successful candidate, you will:

  • Isolate and culture immune cells In vitro
  • Perform CRISPR/Cas9-mediated gene editing
  • Run multicolor flow cytometry and analysis
  • Execute ELISA and/or multiplex cytokine quantification assays
  • Analyze single nucleotide polymorphism genotyping data
  • Perform murine injections, dissection, and processing of pancreas and immune organs for in vivo experiments
  • Process and analyze single cell RNA sequencing data

Your qualifications should include:

  • Bachelor's degree. Masters degree preferred
  • 2+ years of related research/laboratory experience with a Bachelor's degree or 1+ year related research/laboratory experience with a Master's degree.
  • Some experience in the experimental and analytical techniques listed above is preferred, but not required

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

Job ID: 488885812
Originally Posted on: 8/10/2025

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