Downstream Associate Scientist

Downstream Associate Scientist
Location : Seattle, WA
Hours/Schedule : M-F; Standard Business Hours
Compensation : $46.38 - $58.90/hr
Type: Contract

Responsibilities

• Design, execute, and troubleshoot downstream development experiments supporting next-generation lentiviral vector production
• Identify, onboard, and develop novel downstream technologies in collaboration with internal and external partners
• Provide experimental design and executional support to team members
• Support cross-functional development efforts e.g. downstream process development, high-throughput process development
• Perform hands-on experimental work in the early-phase development and optimization of primarily downstream (clarification, chromatography, tangential and normal flow filtration) unit operations for viral vector production
• Work independently and within teams to design, execute, and analyze experiments
• Maintain accurate and detailed laboratory notebook and documentation
• Summarize and present data in group meetings and contribute to group discussions and team strategy
• Author technical reports and study memos

Requirements

• B.S. with 2+ years of experience or M.S. with 0-2 years of hands-on downstream experience
• Experience with Akta Avant chromatography systems and Unicorn software
• Experience with automated and semi-automated filtration systems (Pendotech, Repligen KR2i, Ambr Crossflow, etc)
• Hands-on process development experience
• Independently motivated with ability to multi-task, problem-solve, and coordinate activities within a team
• Ability to design experiments with design of experiment (DOE) approaches, perform experiments, and interpret the results using statistical software (ex. JMP)

Preferred Qualifications:

• Degree in biological or chemical engineering, biochemistry, or bio-related field
• Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing
• Experience with single-use technologies

Benefits
System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.

Ref: #558-Scientific