Scientist / Senior Scientist, Cell Biology

  • Arrowhead Pharmaceuticals, Inc.
  • San Diego, California
  • Full Time

The Position

We are seeking a highly motivated and skilled Cell Biologist to join our dynamic research team focused on developing innovative therapeutic strategies. The successful candidate will play a key role in designing and executing cell-based experiments to support platform development and drug discovery initiatives. This role requires strong hands-on experience in mammalian cell culture, cell sorting, and assay development, along with a solid foundation in cell and molecular biology.

Responsibilities

  • Design, execute, and interpret in vitro cellular assays to support preclinical research and development
  • Maintain and manage various mammalian cell lines under sterile conditions
  • Investigate cellular responses to drug candidates, including internalization, trafficking, and downstream signaling
  • Participate in development and validation of new drug delivery platform
  • Present research findings to cross-function project teams and prepare study reports
  • Perform critical experiments with a high level of productivity and scientific rigor

Requirements:

  • PhD in biology, bioengineering, biochemistry, or a related field
  • Strong expertise in mammalian cell culture and FACS
  • Hands-on experience with high-content imaging, automated liquid handling, or screening platforms
  • Proficiency in developing and executing endpoint and kinetic assays (e.g., luminescence, fluorescence, activity-based, imaging-based)
  • Experience with characterizing ligand-receptor interactions using molecular, cellular, and biochemical approaches
  • Proven ability to adapt to fast pace and evolving research priorities
  • Track record of scientific productivity, including peer-reviewed publications, conference presentations, or patents
  • Additional experience in molecular biology and/or antibody discovery is highly desirable

Preferred

  • Industry or postdoc experience
Job ID: 490359276
Originally Posted on: 8/22/2025

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