Principal Chemist Remote & Hybrid Only Jobs in Massachusetts
A Principal Chemist is a senior professional in the chemistry industry who leads research and development activities, designs and conducts complex chemical experiments, and analyzes the results to develop innovative solutions or new scientific theories. They play a crucial role in synthesizing and characterizing new compounds, developing new tests and methodologies, interpreting data and preparing technical reports, papers, and presentations. They offer technical support to junior chemists and ensure the maintenance of safe laboratory conditions. They are also involved in the development and patenting of new products or techniques.
Important skills for a Principal Chemist include a strong understanding of chemistry principles, analytical thinking, problem-solving, attention to detail, and excellent communication skills. They should have a Doctorate degree in Chemistry or a related field and multiple years of experience in a research setting. Common certifications include the Certified Chemist (CC) and Certified Clinical Data Manager (CCDM). A person may hold roles like Laboratory Technician, Research Chemist or Senior Chemist before ascending to the position of a Principal Chemist.
Principal Scientist, Analytical Development
- Bristol Myers Squibb
- Cambridge, MA
- 1 day ago
- Cambridge, MA
- 1 day ago
Operate and maintain essential instruments such as high-performance liquid chromatography (HPLC) and mass spectrometry. Document and communicate results effectively to team members and leadership....
HybridAS&T Principal Scientist - CGT & Biologics
- Vertex Pharmaceuticals, Inc
- Boston, MA
- 1 day ago
- Boston, MA
- 1 day ago
Job Description General Summary: The Principal Scientist will be part of Analytical Sciences and Technology (AS&T) team within Commercial Manufacturing & Technical Operations (CMTO) department....
Remote HybridSenior Principal Scientist, Neuroscience, Clinical Biomarker, Late Phases, Translational Medicine
- Bristol Myers Squibb
- Cambridge, MA
- 1 day ago
- Cambridge, MA
- 1 day ago
Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable...
HybridSenior Director (Senior Principal Scientist), Translational Medicine, Immunology
- Merck Sharp Dohme
- Boston, MA
- 3 days ago
- Boston, MA
- 3 days ago
Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology Translational Medicine in our Research & Development Division is responsible for planning and managing an...
HybridSenior Principal Scientist, Lab Head Medicinal Chemistry
- Sanofi
- Cambridge, MA
- 11 days ago
- Cambridge, MA
- 11 days ago
Senior Principal Scientist, Lab Head Medicinal Chemistry Employer Sanofi Location Cambridge, Massachusetts Start date May 21, 2026 View more categories View less categories Discipline Science/R D,...
HybridPrincipal Scientist, Drug Substance Process Development & Manufacturing (mAB development focus)
- Generate Biomedicines
- Somerville, MA
- 11 days ago
- Somerville, MA
- 11 days ago
The Role: We are seeking a Principal Scientist, DS Process Development & Manufacturing, to join our growing Drug Substance group at Generate:Biomedicines. This role will support monoclonal...
HybridPrincipal Scientist, Analytical Science and Technology (ASAT), Cell Therapy
- Bristol Myers Squibb
- Devens, MA
- 11 days ago
- Devens, MA
- 11 days ago
Duties/Responsibilities Subject matter expert in Cell Biology and/or Molecular Biology, leads method technical investigation, method optimization/remediations, method transfer and method validation...
HybridPrincipal Scientist, Data Science - Digital Media
- Johnson & Johnson
- Cambridge, MA
- 15 days ago
- Cambridge, MA
- 15 days ago
At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments...
HybridPrincipal Scientist, Discovery BioSciences - Integrative New Targets, Oncology
- Bristol Myers Squibb
- Cambridge, MA
- 24 days ago
- Cambridge, MA
- 24 days ago
biology, and genetic perturbation (eg shRNA, CRISPR, degron tagging of endogenous loci) is required....
HybridMSAT Principal Scientist, Biologics
- Vertex Pharmaceuticals, Inc
- Boston, MA
- 27 days ago
- Boston, MA
- 27 days ago
Job Description General Summary: The Principal Scientist/Engineer, Manufacturing Science and Technology (MSAT) - Biologics & Cell Therapy is a key technical role within the Commercial...
Remote HybridPrincipal Scientist, QC Analytical, Cell Therapy
- Bristol Myers Squibb
- Devens, MA
- 27 days ago
- Devens, MA
- 27 days ago
Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely...
HybridPrincipal Scientist, Quality Control, Bioanalytical Techniques
- Bristol Myers Squibb
- Devens, MA
- 28 days ago
- Devens, MA
- 28 days ago
Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely...
HybridManufacturing Science and Technology Principal Scientist
- Vertex Pharmaceuticals, Inc
- Boston, MA
- 29 days ago
- Boston, MA
- 29 days ago
Job Description General Summary: The incumbent will work cross-functionally with colleagues in the BSMO/CMSC, Regulatory, Quality and R&D of Vertex on the design of processes and technologies...
Remote HybridPrincipal Scientist, Cancer Immunology Clinical Translational Research
- Bristol Myers Squibb
- Cambridge, MA
- 30+ days ago
- Cambridge, MA
- 30+ days ago
Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely...
HybridPrincipal Scientist, Computational Biology
- Bristol Myers Squibb
- Cambridge, MA
- 30+ days ago
- Cambridge, MA
- 30+ days ago
Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely...
HybridDemographic Data for Massachusetts
Moving to Massachusetts? Find some basic demographic data about Massachusetts below.
Principal Chemist Online Courses and Training Opportunities
Title Synonyms
Users interested in this job title also searched for the following job titles
Salary for Principal Chemist Jobs in Massachusetts
Required or preferred licenses and certifications for Principal Chemist positions.
Highest Education Level
Principal Chemists in Massachusetts offer the following education backgroundQualifications / Skill Sets
The following top skills are often required or desired to land a Principal Chemist position
- Personal Protective Equipment
- Chromatography
- Method Development
- Liquid Chromatography
- High-Performance Liquid Chromatography
- Analytical Chemistry
- Assay Development
- Scale-Up
- Rheology
- Purification
- Analytical Method Transfer
- Liquid Chromatography Mass Spectrometry
- Medicinal Chemistry
- Cell-Based Assays
- Cell Biology
- Biomarkers
- Proteomics
- Dynamic Light Scattering
- Peptide Synthesis
- Mass Spectrometry
- Clinical Laboratory Operations
- Chemical Characterization
- ICP-MS
- Biochemistry
- Fourier Transform Infrared Spectroscopy
- Organic Chemistry
- Drug Development
- Ultra Performance Liquid Chromatography
- Drug Discovery
- Experimental Design
- Cell Culture
- Molecular Biology
- Toxicology
- Immunology
- Laboratory Management
- Research and Development
- Validation
- Biotechnology
- Biology
- Optimization
- Process Development
- Clinical Trials
- Good Manufacturing Practices
- Hazardous Materials
- Oncology
- Modeling
- Standard Operating Procedures
- Product Development
- Engineering
- Quality Control
- Troubleshooting
- Investigation
- Documentation
- Quality Assurance
- Mentoring
- Implementation
- Reporting
- Data Analysis
- Collaboration
- Education Experience
- Bachelor's Degree
- Regulations
- Research Skills
- Staff Supervision
- Problem Solving
- Scheduling
- Leadership
- Communication Skills
Principal Chemist Related Career Advice Articles
The Path to a Successful Career as an Analytical Chemist
Analytical chemistry careers are exciting, rewarding, and potentially highly lucrative. Learn about analytical chemistry jobs, salaries, and more.
Read article »
5 Best States for Chemistry Jobs
Launching your chemistry career? Find out the best states for chemistry jobs and the best places for chemists to work.
Read article »
Volunteer Chemistry Opportunities
Volunteering usually calls to mind images of people building houses, serving meals at community kitchens, cleaning up playgrounds and parks, or spending time with the elderly. While these are all worthy causes, you may not realize there are also chemist volunteer opportunities. As a chemistry professional, you have a unique knowledge base and skill set that can make a big difference – whether in a third-world country or your own neighborhood.
Read article »