Principal Scientist Jobs in Collegeville, PA
A Principal Scientist in the chemistry industry is responsible for conducting complex research, developing new procedures, and overseeing a team of scientists to ensure all projects are completed to a high standard. They typically perform experimental tests and analyses, interpreting and presenting results, and preparing research reports and scientific papers. Their work is instrumental in contributing to the development of new products, technologies, or intellectual property. They often work closely with other departments such as Regulatory Affairs, Quality Control, and Manufacturing to ensure all scientific operations meet the necessary standards and regulations.
Important skills for a Principal Scientist include leadership, excellent written and oral communication abilities, strong analytical skills, and the ability to work well in teams. They should have a thorough understanding of various scientific techniques and principles, and be adept at problem-solving. The minimum requirement for this position is typically a PhD in Chemistry or a related field, with substantial experience in the industry. Certifications that can add value include Certified Professional Chemist (CPC) or Certified Clinical Research Professional (CCRP). A person might work as a Research Scientist, Senior Scientist, or Project Leader before moving into the role of a Principal Scientist.
Associate Principal Scientist, Biology-Discovery
- Merck Company
- West Point, PA (6 miles from Collegeville, PA)
- 11 hours ago
- West Point, PA (6 miles from Collegeville, PA)
- 11 hours ago
Immunology, Infectious Disease, Laboratory Automation, Laboratory Safety, Mammalian Cell Culture, Molecular Biology, Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics, Pharmacotherapy, Professional...
In PersonSite Name: USA - Pennsylvania - Upper Providence Posted Date: Jun 2 2026 Principal Scientist, (NMR Spectroscopist) At GSK, we have bold ambitions for patients, aiming to positively impact the health...
In PersonAssociate Principal Scientist, Health Economics
- Lumen
- Upper Gwynedd, PA (7 miles from Collegeville, PA)
- 2 days ago
- Upper Gwynedd, PA (7 miles from Collegeville, PA)
- 2 days ago
We have an exciting opportunity for an Associate Principal Scientist, Health Economics to join our team in London, UK, or West Point, PA, USA....
In PersonSenior Clinical Director (Senior Principal Scientist), Clinical Research, RCC
- Merck Sharp Dohme
- North Wales, PA (9 miles from Collegeville, PA)
- 3 days ago
- North Wales, PA (9 miles from Collegeville, PA)
- 3 days ago
The Senior Clinical Director (Senior Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed medicines in the Late Stage Oncology...
HybridAssociate Principal Scientist, Health Economics
- Merck Sharp Dohme
- West Point, PA (6 miles from Collegeville, PA)
- 3 days ago
- West Point, PA (6 miles from Collegeville, PA)
- 3 days ago
We have an exciting opportunity for an Associate Principal Scientist, Health Economics to join our team in London, UK, or West Point, PA, USA....
HybridPrincipal Scientist, Drug Product Steriles Primary Packaging
- GSK, Plc.
- Collegeville, PA
- 4 days ago
- Collegeville, PA
- 4 days ago
Site Name: USA - Pennsylvania - Upper Providence Posted Date: May 21 2026 Principal Scientist, Drug Product Steriles Primary Packaging Onsite role located at Upper Providence, PA At GSK, we have bold...
In Person- Quest Diagnostics Incorporated
- West Norriton, PA (3 miles from Collegeville, PA)
- 6 days ago
- West Norriton, PA (3 miles from Collegeville, PA)
- 6 days ago
Category Laboratory Location West Norriton, Pennsylvania Job function Operations Job family Laboratory Operations Shift Day Employee type Regular Full-Time Work mode Hybrid Job Description...
In PersonDirector / Principal Scientist, Biologics Drug Substance Commercialization (BDSC)
- Merck Company
- West Point, PA (6 miles from Collegeville, PA)
- 7 days ago
- West Point, PA (6 miles from Collegeville, PA)
- 7 days ago
Join Our Team as a Principal Scientist/ Director in Biologics Drug Substance Commercialization!...
In PersonSenior Principal Scientist, Tech Ops (CMC Science) - Recombinant
- CSL
- King of Prussia, PA (6 miles from Collegeville, PA)
- 12 days ago
- King of Prussia, PA (6 miles from Collegeville, PA)
- 12 days ago
S enior Principal Scientist, TechOps (CMC Science) Recombinant This role is Global and can be based in Bern, CH, Marburg DE, King od Prussia, PA USA or Kankakee IL USA Job Purpose The Senior Principal...
In Person- Merck Company
- West Point, PA (6 miles from Collegeville, PA)
- 13 days ago
- West Point, PA (6 miles from Collegeville, PA)
- 13 days ago
To accomplish the above, the successful candidate must be a creative and innovative scientist with strong organic synthesis, problem-solving, interpersonal, collaboration, and communication skills....
In PersonPrincipal Scientist, Stat. Programming - A&R Standards, Innovation (Hybrid)
- Merck Sharp Dohme
- North Wales, PA (9 miles from Collegeville, PA)
- 13 days ago
- North Wales, PA (9 miles from Collegeville, PA)
- 13 days ago
In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company's renowned Research and Development division, quantitative scientists, in partnership with...
HybridPrincipal Scientist, Stat. Programming - A&R Standards, Innovation (Hybrid)
- Merck Company
- Upper Gwynedd, PA (7 miles from Collegeville, PA)
- 15 days ago
- Upper Gwynedd, PA (7 miles from Collegeville, PA)
- 15 days ago
Job Description In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company's renowned Research and Development division, quantitative scientists, in...
HybridPrincipal Scientist, Data Science - Digital Media
- Johnson & Johnson
- Spring House, PA (10 miles from Collegeville, PA)
- 15 days ago
- Spring House, PA (10 miles from Collegeville, PA)
- 15 days ago
Scientist, Data Science The primary location for this position is flexible - Titusville, NJ; Raritan, NJ; Spring House, PA; Cambridge, MA; or San Diego, CA J&J Innovative Medicine develops treatments...
HybridPrincipal Scientist, Lentivirus Upstream Process
- Johnson and Johnson
- Spring House, PA (10 miles from Collegeville, PA)
- 16 days ago
- Spring House, PA (10 miles from Collegeville, PA)
- 16 days ago
Learn more at We are seeking a highly motivated and experienced scientist to join our Lentivirus Small Scale PD team as a Principal Scientist....
In PersonAssociate Principal Scientist, Analytical R&D
- Merck Company
- West Point, PA (6 miles from Collegeville, PA)
- 19 days ago
- West Point, PA (6 miles from Collegeville, PA)
- 19 days ago
Job Description The Associate Principal Scientist position will support our Live Virus Vaccines (LVV) franchise....
In PersonDemographic Data for Collegeville, PA
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Principal Scientists in Collegeville, PA offer the following education backgroundQualifications / Skill Sets
The following top skills are often required or desired to land a Principal Scientist position
- Personal Protective Equipment
- Chromatography
- Method Development
- Liquid Chromatography
- High-Performance Liquid Chromatography
- Analytical Chemistry
- Assay Development
- Scale-Up
- Rheology
- Purification
- Analytical Method Transfer
- Liquid Chromatography Mass Spectrometry
- Medicinal Chemistry
- Cell-Based Assays
- Cell Biology
- Biomarkers
- Proteomics
- Dynamic Light Scattering
- Peptide Synthesis
- Mass Spectrometry
- Clinical Laboratory Operations
- Chemical Characterization
- ICP-MS
- Biochemistry
- Fourier Transform Infrared Spectroscopy
- Organic Chemistry
- Drug Development
- Ultra Performance Liquid Chromatography
- Drug Discovery
- Experimental Design
- Cell Culture
- Molecular Biology
- Toxicology
- Immunology
- Laboratory Management
- Research and Development
- Validation
- Biotechnology
- Biology
- Optimization
- Process Development
- Clinical Trials
- Good Manufacturing Practices
- Hazardous Materials
- Oncology
- Modeling
- Standard Operating Procedures
- Product Development
- Engineering
- Quality Control
- Troubleshooting
- Investigation
- Documentation
- Quality Assurance
- Mentoring
- Implementation
- Reporting
- Data Analysis
- Collaboration
- Education Experience
- Bachelor's Degree
- Regulations
- Research Skills
- Staff Supervision
- Problem Solving
- Scheduling
- Leadership
- Communication Skills
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