Principal Scientist Jobs in Philadelphia, PA

A Principal Scientist in the chemistry industry is responsible for conducting complex research, developing new procedures, and overseeing a team of scientists to ensure all projects are completed to a high standard. They typically perform experimental tests and analyses, interpreting and presenting results, and preparing research reports and scientific papers. Their work is instrumental in contributing to the development of new products, technologies, or intellectual property. They often work closely with other departments such as Regulatory Affairs, Quality Control, and Manufacturing to ensure all scientific operations meet the necessary standards and regulations.

Important skills for a Principal Scientist include leadership, excellent written and oral communication abilities, strong analytical skills, and the ability to work well in teams. They should have a thorough understanding of various scientific techniques and principles, and be adept at problem-solving. The minimum requirement for this position is typically a PhD in Chemistry or a related field, with substantial experience in the industry. Certifications that can add value include Certified Professional Chemist (CPC) or Certified Clinical Research Professional (CCRP). A person might work as a Research Scientist, Senior Scientist, or Project Leader before moving into the role of a Principal Scientist.

1-15 of 26 Jobs

Principal Scientist, Clinical Research, GI cancer

  • North Wales, PA (17 miles from Philadelphia, PA)
  • 2 days ago
  • North Wales, PA (17 miles from Philadelphia, PA)
  • 2 days ago

The Director (Principal Scientist) has primary responsibility for the planning and directing of clinical research activities involving new or marketed Oncology medicines....

Senior Principal Scientist, Clinical Research, Neuroscience

  • Upper Gwynedd, PA (20 miles from Philadelphia, PA)
  • 2 days ago
  • Upper Gwynedd, PA (20 miles from Philadelphia, PA)
  • 2 days ago

Our Clinical and Pharmacovigilance teams manage studies to provide the safety and efficacy data required for regulatory approval of potential new drugs, vaccines and new indications for existing...

Principal Scientist, Protein Design and Informatics

  • Collegeville, PA (21 miles from Philadelphia, PA)
  • 5 days ago
  • Collegeville, PA (21 miles from Philadelphia, PA)
  • 5 days ago

Site Name: USA - Pennsylvania - Upper Providence, UK - Hertfordshire - Stevenage, USA - California - San Francisco, USA - Massachusetts - Cambridge Posted Date: Jul 7 2025 As Principal Scientist, in...

Principal Scientist, In Silico Discovery - Biologics

  • Spring House, PA (16 miles from Philadelphia, PA)
  • 9 days ago
  • Spring House, PA (16 miles from Philadelphia, PA)
  • 9 days ago

Job title Principal Scientist, In Silico Discovery - Biologics Function Discovery & Pre-Clinical/Clinical Development Sub function Biological Research Category Principal Scientist, Biological Research...

Laboratory Manager

  • Doylestown, PA (24 miles from Philadelphia, PA)
  • 9 days ago
  • Doylestown, PA (24 miles from Philadelphia, PA)
  • 9 days ago

Job Summary: Delaware Valley University invites applications for a Laboratory Manager who will also serve as the Chemical Hygiene Officer for the institution to start in the Fall 2025 semester....

Laboratory Manager

  • Philadelphia, PA
  • 10 days ago
  • Philadelphia, PA
  • 10 days ago

Job Details Laboratory Manager Job Description Organizes and directs the daily activities of a laboratory, supervises subordinates to ensure quality control and compliance with relevant policies...

Job Details Reporting to the divisional Laboratory Director, the Laboratory Manager plans, directs, and supervises all administrative, technical, and fiscal aspects of the Reporting to the...

Associate Principal Scientist, Upstream Drug Substance SME

  • West Point, PA (18 miles from Philadelphia, PA)
  • 10 days ago
  • West Point, PA (18 miles from Philadelphia, PA)
  • 10 days ago

Job Description As part of Our Companys Manufacturing Division, within the Bioprocess Drug Substance Commercialization (BDSC), the Cell Culture and Fermentation Sciences (CCFS) department provides...

Senior Principal Scientist, In Silico Discovery - Biologics

  • Spring House, PA (16 miles from Philadelphia, PA)
  • 10 days ago
  • Spring House, PA (16 miles from Philadelphia, PA)
  • 10 days ago

Job title Senior Principal Scientist, In Silico Discovery - Biologics Function Discovery & Pre-Clinical/Clinical Development Sub function Biological Research Category Senior Principal Scientist, Biological...

Associate Principal Scientist (Associate Director) - Outcomes Research (Lung)

  • North Wales, PA (17 miles from Philadelphia, PA)
  • 11 days ago
  • North Wales, PA (17 miles from Philadelphia, PA)
  • 11 days ago

Associate Principal Scientist (Associate Director) - Oues Research (Lung) Associate Principal Scientist (Associate Director) - Oues Research (Lung) remote type Hybrid locations USA - Pennsylvania -...

Associate Principal Scientist (Associate Director) - Outcomes Research (Lung)

  • Upper Gwynedd, PA (20 miles from Philadelphia, PA)
  • 12 days ago
  • Upper Gwynedd, PA (20 miles from Philadelphia, PA)
  • 12 days ago

Job Description Job Description: This position resides within our company's Value and Implementation (V&I), Outcomes Research organization, which is responsible for real-world evidence generation...

Principal Scientist (Director) - Regulatory Affairs-CMC

  • North Wales, PA (17 miles from Philadelphia, PA)
  • 13 days ago
  • North Wales, PA (17 miles from Philadelphia, PA)
  • 13 days ago

Director, Combination Product Regulatory CMC - (R5) This Principal Scientist position is equivalent to a Director position....

Senior Principal Scientist, Computational Pathobiologist

  • Spring House, PA (16 miles from Philadelphia, PA)
  • 15 days ago
  • Spring House, PA (16 miles from Philadelphia, PA)
  • 15 days ago

Job title Senior Principal Scientist, Computational Pathobiologist Function Discovery & Pre-Clinical/Clinical Development Sub function Nonclinical Safety Category Senior Principal Scientist, Nonclinical...

Associate Principal Scientist Statistical Programming

  • North Wales, PA (17 miles from Philadelphia, PA)
  • 15 days ago
  • North Wales, PA (17 miles from Philadelphia, PA)
  • 15 days ago

In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our Company's renowned Research and Development division, quantitative scientists, in partnership with...

Principal Scientist, Clinical Research, Prostate Cancer

  • Upper Gwynedd, PA (20 miles from Philadelphia, PA)
  • 19 days ago
  • Upper Gwynedd, PA (20 miles from Philadelphia, PA)
  • 19 days ago

Job Description The Director (Principal Scientist) has primary responsibility for the planning and directing clinical research activities involving new or marketed Oncology medicines....

Demographic Data for Philadelphia, PA

Moving to Philadelphia, PA? Find some basic demographic data about Philadelphia, PA below.


Local
National
1,604,167
30,077
Large

Principal Scientist Online Courses and Training Opportunities

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Title Synonyms

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Salary for Principal Scientist Jobs in Philadelphia, PA

Estimated salary range based on data from US Bureau of Labor Statistics (BLS) and iHireChemists research efforts.

Licensing / Certification

Required or preferred licenses and certifications for Principal Scientist positions.



Highest Education Level

Principal Scientists in Philadelphia, PA offer the following education background
Doctorate Degree
47.9%
Bachelor's Degree
28.0%
Master's Degree
22.5%
Associate's Degree
0.7%
High School or GED
0.5%
Vocational Degree or Certification
0.3%
Some College
0.1%
Some High School
0.0%

Average Work Experience
Here's a breakdown of the number of years' experience offered by Principal Scientists in Philadelphia, PA
None
32.8%
Less than 1 year
18.1%
1-2 years
16.9%
4-6 years
11.4%
6-8 years
7.8%
2-4 years
7.0%
10+ years
6.0%

Qualifications / Skill Sets

The following top skills are often required or desired to land a Principal Scientist position


In-Demand skills () are the most popular among employers according to the current jobs in our database. Last updated today!

Other Career Titles

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