Senior Associate Scientist, Molecular Biology, Contractor

Generation Bio is a biotechnology company changing what is possible for people living with T cell-driven autoimmune diseases. The company is developing novel therapeutics leveraging its T cell selective cell-targeted lipid nanoparticle (ctLNP) to deliver siRNA in vivo, enabling modulation of T cell activity that causes inflammation and auto-reactive tissue destruction. By selectively modulating T cells that drive disease pathology, ctLNP-siRNA therapeutics could potently block target function with sequence-level specificity while sparing the broader immune system. This potent new modality is designed to reach targets that are poorly drugged by other approaches, opening a broad indication space of T cell driven autoimmune diseases.

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SUMMARY:

Generation Bio is seeking an energetic and motivated Senior Associate Scientist to support siRNA research and development as part of the Molecular Biology team. The successful candidate will have broad experience executing molecular and cellular biology workflows. Specific workflows relevant to this position include siRNA material processing and inventory, next generation sequencing library construction, expression-based in vitro cell assays. This is a lab-based position that requires strong individual contributions as well as an ability to work well within cross-functional teams.

RESPONSIBILITIES:

• Oversee and execute siRNA material processing, QC and inventory tasks
• Support in-house execution of RNA-seq workflows including RNA purification, NGS library construction and sequencing
• Support siRNA screening workflows including routine cell culture, transfection and expression-based endpoints
• Accountable for on-time execution of experimental projects and workflows
• Communication of results in written and oral form to the functional team lead and broader cross functional teams as needed

QUALIFICATIONS:

• BS in Biology, Biochemistry, Molecular Biology, or related field with a minimum of 2 years of experience or a MS
• Minimum 2 years of relevant laboratory experience
• Experience with molecular biology techniques (e.g. Small-volume pipetting and sample manipulation, RNA purification, PCR, NGS library construction)
• Experience with cell biology techniques (e.g. cell culture, transfection, expression endpoint assays)
• Experience with ELN and inventory management (E.g. Benchling) is a plus
• Excellent organizational skills and detail-oriented focus
• Strong communication and interpersonal skills

POSITION: 6 month contract

EEOC Statement: Generation Bio believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race (to include traits historically associated with race including, but not limited to, hair texture, hair type, hair length, and protective hairstyles such as braids, locks, twists, hair coverings, and Bantu knots), color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Generation Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.