Associate Scientist In Vivo Immunology

Associate Scientist, In Vivo Immunology

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At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.

We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why weve invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSKs long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.

The Associate Scientist in the in vivo immunology team will support the project team in spearheading GSKs innovation of novel viral vaccines and platform programs. You will have the opportunity to work on the in vivo efforts on multiple viral vaccine programs and platforms within GSK and with external partners in a collaborative and matrix team. You will assist in writing in vivo study protocols, coordinate and initiate preclinical studies, conduct and analyze experimental results pertaining to the understanding of cellular mediated immune response and humoral immune response from novel vaccine candidates, formulations, and RNA platforms.

Key Responsibilities:

This role will provide you with the opportunity to lead key activities and to progress your career based on performance. The responsibilities include the following:

• Conduct dosing and tissue harvest from animal studies
• Understand and execute in vivo study protocols, ensuring adherence to GSK and regulatory requirements for compliance with IACUC guidelines
• Perform experiments characterizing cell-mediated immune response for preclinical immunogenicity or challenge studies using flow cytometry, ELISPOT assays and others.
• Analyze experimental data and document them in detail using an electronic notebook
• Write detailed protocols, procedures and work instructions to support immunology assays.
• Contribute to the writing of technical sections of internal and external reports and contribute to scientific papers and patents
• Help develop new experimental techniques based on project needs
• Report results in team meetings, cross-function and cross-department meetings
• Help with Lab management tasks including the ordering of materials, participation in operational meetings, routine equipment maintenance

The successful applicant may spend 2-3 months within the first year in Rockville, MD to support and guarantee a smooth transition of methods and know-how to the new laboratories in Cambridge, MA

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Bachelors degree in Immunology, Virology, Microbiology, Pharmaceutical Sciences, or related scientific field with 2+ years of lab experience.
• Experience working with aseptic techniques
• Experience with laboratory notebook keeping

Preferred Qualifications:

If you have the following competencies, it would be a plus:

• MS degree
• One or more years of experience in conducting in vivo animal studies within the fields of vaccines, infectious diseases, or immunology.
• One or more years of experience in small rodent handling and drug administration, in-study blood sampling, necropsy, tissue harvest, and processing.
• One or more years of experience in designing, executing, and analyzing cell-mediated immune response readouts using conventional or spectral flow cytometry.
• A collaborative team player with strong interpersonal skills to work with diverse groups within the organization.

• Experience with multiple immune-response related readout methods such as ELISA, ELISPOT, Luminex, and qPCR methodologies.
• Proficient in using Microsoft Suite
• Excellent communication and writing skills.
• Extremely organized with experience in documentation of study protocols and reports.

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Please visit GSK US Benefits Summary t o learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose to unite science, technology and talent to get ahead of disease together so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, its also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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