Contract Opportunity: Scientist (Level TBD) in Single Cell Omics
We are seeking a dynamic and highly skilled scientist with expertise in single cell omics data generation and cell handling to support critical initiatives within our Data, AI, and Genome Sciences department in Cambridge, MA.
This contract position requires exceptional interpersonal and problem-solving abilities, along with a proven track record of collaboration in cross-functional teams.
You will be instrumental in supporting innovative single cell omics workflows and applying advanced single cell assays to enhance discovery and validation processes.
Key Responsibilities:
Prepare high-quality cell and nuclei samples for single cell assays.
Design and execute large-scale workflows for single cell assays, focusing on cell preparation and library generation across various platforms using automation (e.g., 10X Genomics 3/5 and Flex assays, Parse, Scale Bio, etc.).
Perform library quantification and sequencing of single cell libraries utilizing Illumina platforms (e.g., NovaSeq).
Collaborate closely with experimental biologists to address biological inquiries, develop workflow strategies, and formulate experimental plans.
Clearly communicate and document assay procedures and workflows for both computational and experimental teams through comprehensive reports and presentations, facilitating efficient analysis and planning.
Keep abreast of the latest developments in single cell technologies, computational techniques, and relevant biological disciplines.
Ensure meticulous documentation of workflows and experimental results.
Quals--
Educational Background:
A Masters or Ph.D. in Biological Sciences or a closely related field, complemented by relevant practical experience as outlined below.
Core Experience and Skills:
A minimum of two (2) years of hands-on research experience focused on cell preparation for single cell transcriptomics and multi-omics, including library creation and quality assessment for diverse sample types.
Proficiency in using automation tools for library creation and sample processing.
A thorough understanding of the data requirements necessary for single cell transcriptomics.
A solid background in single cell data analysis is advantageous.
Direct experience with various single cell profiling technologies (e.g., 10X Genomics 3/5 and Flex assays, Parse, Scale Bio, etc.).
Experience in cell culture and cell handling.
Personality:-
Strong problem-solving abilities, critical thinking skills, and analytical expertise.
Excellent communication skills, both written and verbal, with the ability to convey complex technical information to a wide range of audiences.
Ability to work effectively both independently and as part of a multidisciplinary team.
Preferred Qualifications:
Experience in analyzing single cell transcriptomic data.
Familiarity with specific biological areas related to immune-mediated or metabolic diseases.
Experience in designing workflows for single cell assays.
A strong publication history in reputable peer-reviewed journals.
Note:
100% onsite role.
At least 2 years of experience focusing just on single cell experience.
We are 100% looking for wet lab expertise on single cell experience, library generation
Cell handling for single cell
Library gene.
NGS library prep
10X Genomics is required, Parse, Scale Bio is nice to have
Bioinformatics is nice to have
Single cell transcriptomic, no spatial experience is required.
Job ID: 479383852
Originally Posted on: 6/2/2025
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