- The scientist will be responsible to run in vitro primary cell culture in 96-well plate format, perform serial dilutions of drug molecules, and perform FACS flow cytometry analysis to look at cell populations changes and cell phenotype changes.
- It will be ideal to have candidates with previous mRNA LNP drug candidate screening experience.
- Master with 5-7 year experience level/or PhD preferred
- In vitro primary cell culture (human PBMC, Cyno PBMC and mouse splenocyte)
- Serial dilutions of drug molecules and application of treatment using multichannel pipette
- Live/Dead and antibody staining of cells and FACS flow cytometry run on BD FACS Canto II / Fortessa / LSR II and data analysis using FlowJo software
- mRNA LNP candidate screening
- primary cell culture
- PBMC
- Fibroblasts
- T-Cells
- B-cells
- NK Cells
- LNP
- Lipid Nano Particles
- splenocyte
- FACS
- Flow cytometry
- multichannel pipette
- serial dilution
Job ID: 482710656
Originally Posted on: 6/25/2025
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