Principal Associate Scientist - Protein Biochemistry

Scientist - BioDesign Protein Biochemistry

The BioDesign Protein & Cell Engineering group at our client is seeking a creative and self-motivated scientist to contribute to our mission to design and develop medicines to transform patients' lives. The successful candidate will play a key role in enabling the generation of antibodies and antibody-oligonucleotide conjugates intended to improve the delivery of therapeutic oligonucleotides to target tissues. Primary responsibilities will include antibody expression, cell line generation, target binding and assessment of gene knockdown.

location: Cambridge, Massachusetts
job type: Contract
salary: $35 - 45 per hour
work hours: 9 to 5
education: Masters

responsibilities:
Primary responsibilities will include:

• Stable cell line generation
• Antibody expression in mammalian cells in shake flask cultures up to 3 liter
• Plasmid production
• qPCR to assess target knockdown in cell lines and tissue lysates
• Assessment of antibody binding to target by flow cytometry

qualifications:
Required Skills:

• Mammalian tissue culture experience
• Excellent written and verbal communication, documentation and record-keeping skills
• MS in Biology, Molecular Biology, Cell Biology, Biochemistry or related field with 3 or more years of experience (Candidates with more or less experience will be considered and are encouraged to apply)

Preferred Skills:

• Experience with protein or antibody expression in CHO cells by transient transfection
• Experience with generating stable CHO cell pools secreting recombinant proteins or antibodies
• Experience with large scale expression or bioreactor handling
• Experience with cell engineering, stable cell line generation
• Nucleic acid quantitation by qPCR or ddPCR
• Flow cytometry sample preparation and data analysis
• Immunoassay techniques Eg. MSD, Elisa
• Antibody purification

#LI-KH1

skills: Molecular Biology, Cell Biology, Immunoassays, Flow Cytometry, Cell Cultures

Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact ....

Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).

This posting is open for thirty (30) days.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.