Scientist III

Advance the Future of Immune Cell Profiling in Genetic Medicine

Position: Scientist - In Vitro Immunology & Flow Cytometry

Location: Cambridge, MA| Department: Genetic Medicine / Immunology

Are you passionate about cutting-edge immunology and drug discovery? We're seeking a highly skilled and motivated Scientist to join our dynamic team focused on evaluating mRNA-LNP drug candidates using primary immune cell models and high-dimensional flow cytometry.

This is a hands-on, lab-based role ideal for someone who thrives in a fast-paced, collaborative environment and is excited to contribute to the development of next-generation therapeutics.

What You'll Do

• Perform in vitro primary cell culture using human PBMCs, cynomolgus monkey PBMCs, and mouse splenocytes in 96-well plate formats.
• Conduct serial dilutions of drug candidates and apply treatments using multichannel pipettes.
• Execute flow cytometry assays including Live/Dead staining and antibody panels on BD FACS Canto II, Fortessa, and LSR II instruments.
• Analyze flow cytometry data using FlowJo to assess cell population shifts and phenotypic changes.
• Support mRNA-LNP screening efforts by evaluating immune responses and cellular uptake in primary immune cells.

What You Bring

• M.S. in Immunology, Cell Biology, or a related field with 5-7 years of relevant experience, or Ph.D. with hands-on expertise in primary immune cell assays.
• Strong experience in flow cytometry, including panel design, staining, instrument operation, and data analysis.
• Proficiency in primary immune cell culture and handling of human and animal-derived cells.
• Experience with mRNA-LNP drug screening is highly desirable.
• Excellent organizational skills, attention to detail, and ability to work independently and collaboratively.

If interested, please reach out directly to Lindsee Allienello at lallienello @ actalentservices.com.

Pay and Benefits

The pay range for this position is $65.00 - $70.00/hr.

Eligibility requirements apply to some benefits and may depend on your job

classification and length of employment. Benefits are subject to change and may be

subject to specific elections, plan, or program terms. If eligible, the benefits

available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a fully onsite position in Cambridge,MA.

Application Deadline

This position is anticipated to close on Jul 4, 2025.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email ... for other accommodation options.