Contract Senior Research Associate, Proteomics

In this role you will

• Execute experiments to inform target engagement on transcription factors using a variety of approaches which include tissue cell culture, automated workflows and characterization using mass-spectrometry based proteomics
• Execute high-throughput global proteomics characterization of transcription factors using isotope labeling, TMT, alternative proteases, targeted proteomics (PRM or equivalent) label-free workflows
• Generate data in a timely manner; support lead discovery initiatives and regularly contribute at the bench
• Work closely with senior staff to set experimental strategy, project goals, and timelines to drive projects toward successful completion
• Work closely with biology, biochemistry, chemistry and compound management teams in early discovery to optimize screening on high-value transcription factors

About you

• You have a B.S or M.S in chemoproteomics, chemical biology, biochemistry or analytical chemistry
• You have 1-3 years of experience in industry
• You have knowledge of proteomics principles and hands-on experience in mass spectrometry-based quantitative proteomics that includes DDA, DIA and/or LFQ
• You may have experience in targeted proteomics and TMT-based workflows,
• You may also have understanding of proteomics sample preparations using both 96- and 384-well plate formats using SP3
• You may have prior experience with assay development, sample prep automation, HPLC fractionation
• You have a desire to work in a lab-based role within a highly adaptive, fast-paced collaborative environment and can creatively solve problems through innovation and communication
• You have self-motivation, great decision making, organizational, analytical, interpersonal and communication skills

This is a 6 month contract position through end of year 2026 with possibility for extension.

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