Principal Scientist, Analytical Development, Cell Therapy

Working with Us
Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

Position Summary
We are looking a highly motivated and self-driven professional to join our Cell Therapy Analytical Development (CTAD) department as a Senior or Principal Scientist. The successful candidate will play a crucial role in developing, validating, transferring, and troubleshooting plate-based assays to advance cell therapy development deliverables.

The highly experienced assay developer will independently develop and execute plate-based assays to support process development, as well as the characterization and release of autologous and allogenic cell therapies which are undergoing clinical trials. The Senior/Principal Scientist will design and analyze experiments with minimal supervision, leading to the development of robust analytical methods. They will be responsible for developing QC methods for lot release testing, characterization methods for product understanding, and routine testing to support process development and comparability assessments.

The Senior/Principal Scientist should possess significant hands-on experience in ligand binding/antibody assay development and demonstrate capability in collaborating with other groups, such as discovery research, product sciences, process development, and QC. Additional preferred experience includes working in a cGMP environment and/or performing analytical method validation and transfers to a QC facility. The ideal candidate will be passionate about developing novel medicines, thrive in an intellectually challenging environment, and enjoy collaborating with a team of like-minded Scientists. This is a lab-based position, with the level commensurate with experience.

Key Responsibilities

• Act as subject matter expert to develop, optimize, validate, and troubleshoot assays used for vector and cell therapy products.
• Design and execute phase appropriate validation, and manage method transfer from CTAD to internal or external QC/testing groups.
• Maintain meticulous laboratory notebooks and manage routine sample analysis requests.
• Represent the group and present data to cross functional meetings.
• Author, review and approve technical documents, including methods, protocols, reports, and regulatory submissions.
• Good knowledge of cGMP and ICH/FDA/EMEA guidance.
• Facilitate smooth operation of the laboratory, including ordering, assisting in the cryopreservation of cellular material, sample management, etc.
• Complete regulatory, site, and department training requirements on a timely basis.

Qualifications & Experience

• A PhD with 5+ (BS with 12+) years of experience in pharmaceutical research, development, or related industry experience.
• In-depth knowledge and hands-on experience in development and validation of ligand binding assays (e.g., ELISA, MSD, AlphaLISA, Simple Plex, Luminex).
• Proven experience with data analysis and interpretation using software (e.g., Softmax Pro, Gen5, MSD Workbench, Excel).
• Ability to work effectively in a collaborative team setting and in a rapidly changing environment with frequent changes in priorities, which require strong organizational skills.
• Strong written and oral communication skills.
• Experience in cGMP environment is a preferred.

The starting compensation for this job is a range from $127,000 - $159,000,

plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and the geographic location where work is performed. Final, individual compensation is decided commensurate with demonstrated experience. For more on benefits, please visit our BMS Careers Site. Eligibility for specific benefits listed therein may vary based on job and location.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Years holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

If you come across a role that intrigues you but doesnt perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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