Associate Scientist I - In Vitro Pharmacology

About the Department

Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Seattle reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

The Position

The Associate Scientist I will be responsible for strategy implementation and operations for conducting and summarizing non-clinical in vitro studies internally and externally in the support of new drug evaluations. Design, coordinate, and report pre-clinical pharmacokinetic and pharmacodynamic in vitro experiments within research projects as part of target validation, target maturation, or mode-of-action studies. Develop and improve in vitro models supporting non-clinical studies, take an active role in research projects, and contribute to innovation by identifying and exploring new therapeutic targets and principles. Communicate evaluations and implications of in vitro data internally, externally, and in regulatory submissions as relevant.

Often demonstrates high subject matter knowledge. Sets directions and deliver results in own role which have direct impact within or outside the unit. Provides support on defined issues and contributes through application of expertise and knowledge. Often requires the ability to handle more complex tasks and with few or no defined procedures in place. Problems require solution through a choice between known alternatives, within the area of expertise and direct manager will evaluate the appropriateness and effectiveness of the solution. Might be entirely independent or just need occasional guidance from manager/senior colleagues.

Hands-on work of moderate to high complexity; responsible for recommending timelines for assays & drafting & executing experimental plans to meet study deadlines; provides scientific input to biology or technical challenges or target identification; analyses & interprets data of moderate complexity with limited input from supervisor; makes independent decisions related to day to day experimental activities; develops, optimizes, & drafts protocols for methods of moderate complexity with no input from supervisor, activities of high complexity with reduced input; presents ideas & data to team, site, & global project teams; May mentor or directly supervise less experienced team members based on business need, skill, and/or interest.

Relationships

Reports to of the head of the related research area.

Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments at Novo Nordisk; & frequent interaction with project managers & other colleagues in Denmark.

Individual may interact with external research collaborators both academia- & industry-based.

Essential Functions

• Designing and coordinating pre-clinical in vitro experiments
• Develop experimental protocols for in vitro studies
• Coordinate with internal and external stakeholders to ensure smooth execution of experiments
• Ensure compliance with ethical and regulatory guidelines for animal studies
• Monitor and troubleshoot experimental procedures to ensure data quality and integrity
• Hands on experience working with IPSC-derived neuronal cell models and assays required
• Develop neuronal cell models and functional assays and conduct experiments using these models and assays
• Perform Western blot, QPCR, DNA, RNA and protein extraction from cells and tissues
• Analyze in vitro data using appropriate statistical methods
• Generate comprehensive reports summarizing experimental findings
• Present data to internal teams and external stakeholders
• Provide insights and recommendations based on data analysis
• Contributing to target validation and mode-of-action studies
• Collaborate with cross-functional teams to identify and validate therapeutic targets
• Design and execute in vitro experiments to investigate target function and mechanism of action
• Contribute to the interpretation and integration of in vitro data into overall project strategy

Qualifications

• BS/BA Degree and 4+ years relevant technical experience required; or masters degree and 2+ years relevant experience can be considered
• Expertise in target validation, target maturation, or mode-of-action studies
• Proven experience in developing and improving in vitro models supporting non-clinical studies
• Strong track record of communicating and presenting in vitro data internally, externally, and in regulatory submissions
• Demonstrated ability to contribute to innovation by identifying and exploring new therapeutic targets and principles

The base compensation range for this position is $81,010 to $145,820. Base compensation is determined based on a number of factors. This position is also eligible for a company bonus based on individual and company performance. Novo Nordisk offers long-term incentive compensation and or company vehicles depending on the position's level or other company factors. Employees are also eligible to participate in Company employee benefit programs including medical, dental and vision coverage; life insurance; disability insurance; 401(k) savings plan; flexible spending accounts; employee assistance program; tuition reimbursement program; and voluntary benefits such as group legal, critical illness, identity theft protection, pet insurance and auto/home insurance. The Company also offers time off pursuant to its sick time policy, flex-able vacation policy, and parental leave policy.

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

Were not your typical healthcare company. In a modern world of quick fixes, we focus on solutions to defeat serious chronic diseases and promote long-term health. Our unordinary mindset is at the heart of everything we do. We seek out new ideas and put people first as we push the boundaries of science, make healthcare more accessible, and treat, prevent, and even cure diseases that affect millions of lives. Because it takes an unordinary approach to drive real, lasting change in health.

Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at .... This contact is for accommodation requests only and cannot be used to inquire about the status of applications.

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