Senior Scientist II, ARD

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

AbbVie Analytical Research & Development (Analytical R&D) is a global analytical scientific organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products.Our scope includes AbbVie's diverse pipeline of innovative small molecule and therapeutic biologic medicines and spans from the selection of Discovery candidate molecules to Late Stage Clinical.We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines.Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.We are looking for diverse candidates with strong scientific experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

Position Description:

For the Senior Scientist II position, we are seeking a highly motivated candidate who can conceive, implement and execute novel scientific research and development. Generate new scientific proposals and lead these efforts. Act as a lead scientist in his/her area of expertise and critically evaluate relevant scientific and regulatory advances and integrate this knowledge into research and development programs.

This position will be within Analytical R&D's Screening Lab, which functions as a high-throughput method screening and development group that serves a diverse set of stakeholders and impacts all pipeline programs. The Screening Lab is seeking a Separations Scientist with experience in chromatographic method development for small molecules and biologics. An ideal candidate would have hands-on experience developing methods and troubleshooting difficult separations related challenges. Additionally, He/she should possess an understanding of core discipline and support early phase development of New Chemical Entities (NCEs) and New Biologic Entities (NBEs) for both drug substance and drug product in preclinical and clinical programs.

An ideal candidate will have pharma related project lead experience and have a proven track record of developing novel approaches for method development and solutions for difficult separations. Additional experience with advanced CDS control, process chromatography, and automation, as well as experience with emerging drug modalities (LNPs, Peptides, Oligos, etc.) is desirable. In this dynamic and fast-paced environment, your expertise and insight will ensure that robust and reliable methods enable pipeline projects.

Responsibilities:

• Support high-throughput platform screening capabilities for separation-based assays for small-molecules and biologics (Chiral, Achiral, HILIC, SFC, 2DLC, HIC, IEX, SEC, etc.)
• Development of stability indicating methods using a variety of analytical separation (HPLC/UHPLC) and detection modes (UV, MS, CAD) for active pharmaceutical ingredients.
• Employ chromatographic modeling software (Fusion, Drylab, Chromsword, etc.) for method development and robustness.