Scientist I

  • AbbVie
  • Worcester, Massachusetts
  • Full Time
Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok ( .

Job Description

Purpose

Describe the primary goals, objectives or functions or outputs of this position.

Investigate, identify, develop, and optimize new methods and techniques to generate reliable and reproducible data in a timely manner. Read and adapt scientific literature to accomplish assignments and demonstrate broad and versatile technical expertise within discipline.

Responsibilities

+ Independently design, develop, and optimize robust analytical methods using separations-based techniques (HPLC, icIEF, CE-SDS) to characterize biopharmaceutical products

+ Implement and innovate new experimental protocols/techniques.

+ Understand the goal and maintain a high proficiency in his/her projects as well as the overall program.

+ Interpret results and draw conclusions from own multistage experiments, note significant deviations, then suggest, design, and pursue relevant experiments.

+ Understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner.

+ Perform routine and complex tasks competently and independently and generate reliable and consistent results.

+ Troubleshoot complex analytical issues and implement innovative solutions to improve method performance and efficiency.

+ Impact projects mostly through lab and/or pilot plant based activities.

+ Responsible for compliance with all applicable Corporate and Divisional policies and procedures.

+ Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.

Qualifications

Qualifications

+ Bachelors degree in Biochemistry, Bioengineering, or Pharmaceutical Sciences with 5 years of relevant experience or Masters Degree in Biochemistry, Bioengineering, or Pharmaceutical Sciences or equivalent education with typically two years of experience.

+ Theoretical and practical knowledge to carry out the job functions.

+ Strong understanding of protein biochemistry and analytical method development principles.

+ Experience in developing and optimizing methods for charge variant analysis, including both icIEF and CEX techniques, with the ability to transfer these methods to a QC environment.

+ Proficiency in AKTA purification and fractionation to support comprehensive characterization workflows.

+ Proficiency in operating and troubleshooting analytical instrumentation (e.g., Agilent, Waters HPLC systems, Maurice, PA800 systems).

+ Experience with the qualification and validation of analytical methods in accordance with ICH, FDA, and USP guidelines, ensuring methods are suitable for late-phase development and regulatory submissions.

+ Experience using automation to standardize high-throughput workflows.

+ Familiarity with statistical tools for data analysis, Empower and regulatory guidelines.

+ Experience collaborating with the process development, quality control, and regulatory affairs teams to align analytical strategies with project timelines and goals.

+ Knowledge of AAV separation techniques and awareness of future advancements in the field.

+ Capable of providing technical guidance and mentorship to junior scientists and laboratory staff.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

+ The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

+ We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

+ This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

Job ID: 488289933
Originally Posted on: 8/6/2025

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