Senior Scientist, Translational PK

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok .

Conceive and implement novel experimental approaches to answer scientific questions. Investigate, identify, develop, and optimize new methods and techniques. Contribute to project science in area of expertise. Develop productive collaborations and communications with other groups across science disciplines.

Responsibilities:

• Design and provide scientific oversight of preclinical PK/TK studies
• Conduct data analyses including PK/PKPD analyses, modeling and simulation, literature data analyses
• Liaise with research, toxicology, immunology, bioanalytical, clinical development, and regulatory colleagues to generate data and knowledge supporting product development and implementation of translational models
• At project level, establish and maintain effective collaborations with key stakeholders to facilitate data integration for biomarker selection, candidate nomination/selection, and human dose prediction
• Participate and present at various departmental and cross functional teams
• Author regulatory documents including protocols, study reports, exposure-response analyses reports, relevant section of investigator brochures, common technical documents, white papers, and other similar documents
• Maintain awareness of emerging literature and science in PK and translational sciences specific to eyecare, aesthetics, and neurotoxin.
• Author scientific publications and present at scientific conferences

• Bachelors Degree or equivalent education and typically 10+ years of experience, Masters Degree or equivalent education and typically 8+ years of experience, or PhD (preferably in chemical or biomedical engineering; applied mathematics; quantitative pharmaceutical sciences or a related field or Pharm.D.)with 0-4 years experience.
• Possess thorough theoretical and practical understanding of own scientific discipline.
• Understanding of small or large molecule drug modalities and relevant analytical methods for measuring drug and biomarker levels in preclinical and clinical study samples
• Strong communication skills and the ability to effectively communicate with both internal and external stakeholders, and to audiences of diverse backgrounds
• Highly motivated, self-driven and results-oriented person, capable of both leading and being lead
• High degree of flexibility in adapting to different projects and personalities as well as excellent networking and relationship-building skills (both internal and external)
• Passion for data analysis, solving technical problems and applying new technologies to further scientific goals and answer key scientific questions enabling data informed decision-making

Preferred:

• Hands-on experience with relevant modeling software and programming languages including MATLAB/Simbiology, R, Python, WinNonLin/Phoenix, NONMEM, etc. is desired
• Publication record demonstrating PK/PD or systems modeling examples is highly desired
• Additional prior experience in an experimental in vitro or in vivo biology field is desired

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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