Sr Research Associate, In Vivo Pharmacology

The Position

Earli's platform technology uses cancer-activated gene expression to usurp the dysregulated pathways that lead to malignancy. We are leveraging this platform for the creation of novel immuno-oncology therapeutic approaches to treat cancer. Your work will directly support the in vivo evaluation of these approaches. Within this context, you will:

Your Primary Responsibilities

• Conduct, plan, perform, and analyze rodent in vivoexperiments testing our cancer treatment products
• Administer test agents to mice via multiple routes (IV, PO, IP, SC)
• Assess tumor burden by caliper, bioluminescence, fluorescence and microCT measurements
• Conduct rodent blood collections, surgeries, and necropsies
• Contribute to Biochemical/Molecular analysis of tissues and plasma (i.e. qPCR, Luminex)
• Maintain familiarity with current scientific literature
• Depending on the level of experience, the candidate would be encouraged to lead their own projects and presenting data both internally and at conferences
• Work independently and collaborate with scientific colleagues in support of team goals

Your Required Experience, Knowledge and Skill

• Minimum of 3+ years of industry experience conducting rodent studies to determine efficacy of new therapies
• Must have technical expertise in mouse handling, IV dosing, subcutaneous and orthotopic tumor cell implantation, tissue collection
• Experience in contributing to cancer research questions is required
• Experience with tissue culture and biochemical and/or molecular techniques is an advantage
• Strong communication skills are required
• Strong sense of scientific rigor, integrity, and curiosity are required
• Ability to handle multiple projects simultaneously and meet aggressive project timelines
• Highly organized with reliable time management skills
• Ability to maintain detailed documentation
• Ability to work in a team-oriented and fast-paced environment
• Proficient with basic computer programs routinely used in a lab such as MS Word, Excel, and PowerPoint, GraphPad Prism