Principal Scientist, Biology

  • U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.
  • San Diego, California
  • Full Time
About the role:#LI-OnsiteWe are seeking an innovative and skilled scientist to drive a drug discovery program and interrogate cancer targets using chemically induced proximity approaches. The ideal candidate should have a proven track record of strong scientific achievement in induced proximity research and/or LMW drug discovery. This role involves executing assays and overseeing experiments using biochemical and cellular systems to answer key scientific questions across various stages of drug development.Key Responsibilities:Conceptualizes, plans and leads/coleads novel projects with team and enables matrix collaboration on project to rapidly assess and achieve creative results for impact on Oncology goals.Generates innovative ideas within own team and/or project team/functional community to address technical challenges and/or answer project key scientific/technical/development questions.Establishes key scientific questions, aligns on project timelines, and priorities to enable datadriven advancements within own team as well as the broader project team.Recognizes and leverages innovation opportunities with own team across projects with focus on relevant areas of deep expertise; plans and executes approaches to enable strategic focus areas.Collaborate in cross-functional innovation and discovery initiatives to advance understanding of novel modalities and drive the development of groundbreaking targeting strategies in oncology.Influences and inspires own team and/or brings matrix collaborators together across the organization with eye for progressing teams towards decision points and deepening scientific understanding.Essential Requirements:This position will be located at the La Jolla, CA site and will not have the ability to be located remotely. This position will not require travel.Ph.D. in a relevant scientific discipline with 3+ years post-Ph.D. or relevant industry experienceExpertise in molecular biology, biochemistry, chemical biology, cell biology, induced proximity drug discovery, and/or chemical genomics.Highly organized, quality-focused management style with emphasis on communication and alignment of expectations and timelines.Demonstrable ability to creatively and constructively collaborate with cross-functional colleagues to drive programmatic success.Desirable Requirements:Strong background in structure biology, and/or chemical proteomics as well as leading bench-facing scientists to achieve programmatic goals and develop skills needed for continued growth.Knowledge and experience in moving programs through governance.The pay range for this position at commencement of employment is expected to be between: $108,500 and $201,500 for Principal Scientist I or $119,700 and $222,300/year for Principal Scientist II; however, while salary ranges are effective from 1/1/25 through 12/31/25, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an at-will position and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Job ID: 491061962
Originally Posted on: 8/28/2025

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