Scientist- Analytical Chemistry

  • Hydrogen Group
  • Lexington, Kentucky
  • Full Time
Scientist, Screening & Analytical Chemistry About the Opportunity We are seeking a Scientist in Analytical Chemistry to lead the development of high-throughput analytical workflows supporting their R&D pipeline. This is a hands-on, high-impact role on a tight-knit, multidisciplinary team. What You'll Do The Scientist will develop and optimize analytical methods for targeted metabolite quantification, leading method development on GC/MS, GC-FID, and LC-QQQ-MS platforms. You'll design high-throughput analytical workflows with fast cycle times, develop sample preparation and derivatization strategies, and work alongside automation and screening teams to support microtiter plate-based fermentations. Additional responsibilities include analyzing and interpreting large datasets, mentoring junior staff, interfacing with instrument vendors to maintain uptime and optimal performance, and authoring SOPs and technical reports. Required: PhD in Analytical Chemistry, Chemistry, or related field OR MS with 8+ years or BS with 13+ years of relevant industry experience Strong, demonstrated experience in analytical method development Hands-on expertise developing GC-FID and GC/MS assays for targeted quantitation and metabolite profiling LC/QQQ-MS assay development for targeted quantitation Track record of optimizing assays for speed, sensitivity, and throughput Preferred: High-throughput screening environment experience Integration of analytical workflows with automation and liquid handling platforms Familiarity with LIMS systems (Benchling preferred) and large dataset analysis Industrial biotech or applied R&D background Experience with UHPLC, GC-FID, GC/MS, and LC/QQQ-MS instrumentation Sample extraction and prep across complex matrices (microbial fermentation broth, microbial biomass, purified extracts), including automated approaches What You'll Get Competitive base salary aligned with your experience Equity participation in a high-growth synthetic biology company Comprehensive medical, dental, and vision benefits 401(k) with company match Generous PTO and paid holidays Direct exposure to leadership and a clear path for technical career growth ...
Job ID: 522358982
Originally Posted on: 5/24/2026

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