Senior Research Associate, Discovery Medicine

  • BigHat Biosciences
  • San Mateo, California
  • Full Time
Senior Research Associate, Discovery Medicine

Department: Discovery Medicine

Employment Type: Full Time

Location: San Mateo, CA

Description The role: BigHat Bioscience is looking for a motivated and energetic Senior Research Associate* with a strong background in Immunology, cell culture, flow cytometry and primary cell-based assays to support the characterization of our lead therapeutic candidates.
*At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.

Key Responsibilities
  • Drive the development of therapeutics by owning the functional characterization of therapeutic candidates.
  • Plan, execute, and analyze TDCC, T cell activation, cytokine release, FACS, ELISA, ADCC, and other relevant functional assays.
  • Perform isolation and culture of primary immune cells from blood or tissue.
  • Inform program plans based upon experimental results and make. relevant recommendations for program conceptualization and advancement.
  • Keep detailed and organized records of experimental protocols and results.
  • Proactively and independently interpret and present scientific findings.
  • Collaborate and communicate across a diverse research team to successfully progress scientific goals.


Skills Knowledge and Expertise
  • B.Sc. degree in cell biology, molecular biology, biochemistry, genetics, immunology, or a related field, with at least 3 years of relevant experience, including 1 year in industry.
  • Hands-on proficiency in standard immunology and cell biology techniques such as mammalian cell culture and multicolor flow cytometry.
  • Previous experience with automation and high-throughput assays desired.
  • Scientific curiosity and problem-solving abilities.
  • A strong can-do mentality and desire to thrive in a dynamic start-up environment.
  • The ability to communicate clearly and build open collaborative relationships.


Total Rewards The salary estimated for this position is $100,000 - $115,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave
Job ID: 523242321
Originally Posted on: 6/1/2026

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