Bioinformatics Scientist

Overview

We are seeking a Bioinformatics Scientist to support the National Institutes of Health's (NIH), world renowned National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, MD. Our NIAID professional, technical, and scientific support personnel are part of a preeminent team focused on positively impacting millions of lives around the world with groundbreaking research. Candidates will work at a prominent and vibrant NIAID worksite to directly support exciting ongoing research activities as a contractor team member. Accelerate your career and apply below to help us make a difference.

CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. We combine our proven systems with today's most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs.

Our employees enjoy a collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad.

Responsibilities

• Implement and/or run software(s) for:

• Structural analysis of HIV-1 antibody/antigen complexes

• Antibody resistance analysis for pathogens with high sequence diversity

• Structure-based design to improve antibody potency and breadth for HIV-1 and other pathogens

• Structure-based design of immunogens for HIV-1 and other pathogens

• Statistical analysis of VRC immunization studies for HIV-1 and other pathogens

• Other bioinformatics analysis to assist the missions of Structural Biology and Structural Bioinformatics Core Sections

• Express, purify, and characterize protein designs from the Structural Bioinformatics Core Section

• Determine atomic-level structures for protein designs from the Structural Bioinformatics Core Section

• Assist with creating figures, writing, and proof reading scientific manuscripts.

• Other duties as assigned

Qualifications

• Bachelor degree in Bioinformatics, Biochemistry, or a related discipline is required.
• Minimum of one year of experience with HIV-1 fusion peptide-directed antibody research
• Prior experience in Python or Perl
• Prior experience with protein modeling programs (e.g. PHENIX, ccp4, Coot, etc.)
• Prior experience with protein visualization software (e.g PyMoL or Chimera)
• Prior experience in protein purification
• Prior experience with protein binding assays, such as ELISA and bio-layer interferometry
• Prior experience in X-ray crystallography

Physical Requirements:

The physical requirements described here are representative of those that must be met by a candidate to perform the essential functions of this job. Reasonable accommodations may be provided to enable individuals with disabilities to perform essential job functions.

• Ability to lift or carry 25 - 50 pounds, reach above shoulder level and use both hands.
• Will be required to stand or walk more than 25 of 30 min..
• Must have depth perception, correctable near vision, and distinguish basic colors.
• Ability to work alone and closely with others.

Please submit your resume online at www.CAMRIS.com. CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law.

CAMRIS offers a comprehensive benefits package, including medical, dental, and vision insurance for individuals and families, FSAs, HSA, life and AD&D insurance, short- and long-term disability, legal services, voluntary hospital indemnity, critical illness and accident insurances, EAP, pet insurance, 401(k) with employer match and Roth option, tuition and professional reimbursement, public transportation support in the DMV area, a referral bonus program, vacation with tenure-based increases, PTO, 11 paid holidays, paid bonding leave, and paid supplemental short-term disability.

Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.