Principal Scientist Jobs in Brisbane, CA

A Principal Scientist in the chemistry industry is responsible for conducting complex research, developing new procedures, and overseeing a team of scientists to ensure all projects are completed to a high standard. They typically perform experimental tests and analyses, interpreting and presenting results, and preparing research reports and scientific papers. Their work is instrumental in contributing to the development of new products, technologies, or intellectual property. They often work closely with other departments such as Regulatory Affairs, Quality Control, and Manufacturing to ensure all scientific operations meet the necessary standards and regulations.

Important skills for a Principal Scientist include leadership, excellent written and oral communication abilities, strong analytical skills, and the ability to work well in teams. They should have a thorough understanding of various scientific techniques and principles, and be adept at problem-solving. The minimum requirement for this position is typically a PhD in Chemistry or a related field, with substantial experience in the industry. Certifications that can add value include Certified Professional Chemist (CPC) or Certified Clinical Research Professional (CCRP). A person might work as a Research Scientist, Senior Scientist, or Project Leader before moving into the role of a Principal Scientist.

1-15 of 34 Jobs

Associate Principal Scientist, Respiratory Discovery

  • Merck Company
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 1 day ago
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 1 day ago

We are seeking an Associate Principal Scientist with strong expertise in respiratory biology and translational research to contribute to target discovery, validation, and translational biology strategy...

In Person

Senior Principal Scientist, Neuroscience, Clinical Biomarker, Late Phases, Translational Medicine

  • Bristol Myers Squibb
  • Brisbane, CA
  • 1 day ago
  • Brisbane, CA
  • 1 day ago

R1601688 : Senior Principal Scientist, Neuroscience, Clinical Biomarker, Late Phases, Translational Medicine...

Hybrid

Principal Scientist, Protein Sciences, Analytical Characterizations

  • Valid8 Financial, Inc.
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 2 days ago
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 2 days ago

Principal Scientist, Protein Sciences, Analytical Characterizations September 2025 Department: Technology Position Summary: TCG Labs-Soleil is seeking a highly experienced and driven Principal Scientist...

In Person

Principal Scientist, Computational Chemistry

  • Eikon Therapeutics, Inc.
  • Millbrae, CA (6 miles from Brisbane, CA)
  • 4 days ago
  • Millbrae, CA (6 miles from Brisbane, CA)
  • 4 days ago

Position We seek a Principal Scientist in Computational Chemistry with a demonstrated ability of successfully applying in silico technologies to drive the discovery of quality lead-like molecules against...

In Person

Principal Scientist, Purification Process Development

  • Denali Therapeutics
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 6 days ago
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 6 days ago

Design and execute lab-scale chromatography and filtration studies to inform and support large scale process decisions Maintain existing workflows to provide purification support for cell line and cell...

In Person

Principal Scientist - PKDM, Modeling and Simulation

  • Amgen
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 7 days ago
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 7 days ago

The Principal Scientist we seek is a self-driven, dynamic team member with these qualifications....

In Person

Principal Scientist - Medicinal Chemistry

  • Nurix Therapeutics
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 7 days ago
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 7 days ago

Expert in organic synthesis, knowledgeable of the current literature, with strong synthetic problem-solving skills....

In Person

Principal Scientist, Biomarker Data Sciences

  • Biogen
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 8 days ago
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 8 days ago

About This Role: As a Principal Scientist in Biomarker Data Sciences within the Clinical Biomarkers group at the West Coast Hub, you will lead the charge in multi-omics analyses of extensive clinical...

In Person

Principal Scientist, Process Development

  • Gilead Sciences
  • Foster City, CA (12 miles from Brisbane, CA)
  • 12 days ago
  • Foster City, CA (12 miles from Brisbane, CA)
  • 12 days ago

Job Description Principal Scientist, Purification Development - Pre-Pivotal Biologics Foster City, CA Principal Scientist, Purification Process Development (Pre-Pivotal) will be responsible for leading...

In Person

Principal Scientist - Agentic Product

  • Adobe
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 12 days ago
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 12 days ago

As a Principal Scientist (Engineering), Agentic Product, you will be a key technical leader for Adobe's up-and-coming AI-native experience that brings generative models, creative intelligence, and decades...

In Person

Senior/Principal Scientist In Vivo Pharmacology

  • Kodiak Sciences Inc
  • Palo Alto, CA (22 miles from Brisbane, CA)
  • 13 days ago
  • Palo Alto, CA (22 miles from Brisbane, CA)
  • 13 days ago

Kodiak Sciences is seeking a highly motivated and independent Senior/Principal Scientist to join the In Vivo Pharmacology team....

In Person

Principal Scientist, Cancer Pharmacology, Translational Research

  • Revolution Medicines, Inc.
  • Redwood City, CA (18 miles from Brisbane, CA)
  • 13 days ago
  • Redwood City, CA (18 miles from Brisbane, CA)
  • 13 days ago

The Opportunity: As a Principal Scientist in the Cancer Pharmacology team within the Translational Research group, in the Biomedical Discovery Research Department, you will: Provide scientific and strategic...

Hybrid

Principal Scientist, Clinical Biomarkers

  • Biogen
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 14 days ago
  • San Francisco, CA (6 miles from Brisbane, CA)
  • 14 days ago

About This Role: As a Principal Scientist in Clinical Biomarkers, you will play a pivotal role in the design, execution, and interpretation of biomarker activities across our clinical studies....

In Person

Principal Scientist PKDM (Large Molecule Project Team Representative)

  • Amgen
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 15 days ago
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 15 days ago

Principal Scientist PKDM (Large Molecule Project Team Representative) What you will do Lets do this. Lets change the world....

In Person

Associate Principal Scientist, In Vivo Pharmacology

  • Merck Company
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 15 days ago
  • South San Francisco, CA (2 miles from Brisbane, CA)
  • 15 days ago

Our company's Research Laboratories in South San Francisco is seeking a highly motivated and accomplished Associate Principal Scientist to join our Quantitative Biosciences (Pharmacology) department...

In Person

Demographic Data for Brisbane, CA

Moving to Brisbane, CA? Find some basic demographic data about Brisbane, CA below.


Local
National
4,836
262
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Principal Scientist Online Courses and Training Opportunities

iHireChemists curates thousands of courses in order to recommend the best ones to help further your career. If you register for a course using the links on our site, we may receive a small commission.
Data Scientist Nanodegree Program
This advanced Nanodegree prepares you to tackle data science at scale. Work with AI best practices, build production-ready projects, and gain the confidence to lead data-driven solutions. Our...
Software Engineering for Data Scientists Course
Prepare for advanced data science work with software engineering best practices. Explore OOP, testing, areproducibility, and build a FastHTML dashboard that makes machine learning insights...
Category Theory for Scientists
The goal of this class is to prove that category theory is a powerful language for understanding and formalizing common scientific models. The power of the language will be tested by its ability...

Title Synonyms

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Salary for Principal Scientist Jobs in Brisbane, CA

Estimated salary range based on data from US Bureau of Labor Statistics (BLS) and iHireChemists research efforts.

Licensing / Certification

Required or preferred licenses and certifications for Principal Scientist positions.



Highest Education Level

Principal Scientists in Brisbane, CA offer the following education background
Doctorate Degree
47.7%
Bachelor's Degree
28.2%
Master's Degree
22.6%
Associate's Degree
0.6%
High School or GED
0.5%
Vocational Degree or Certification
0.3%
Some College
0.1%
Some High School
0.0%

Average Work Experience
Here's a breakdown of the number of years' experience offered by Principal Scientists in Brisbane, CA
None
32.8%
Less than 1 year
18.1%
1-2 years
16.9%
4-6 years
11.4%
6-8 years
7.8%
2-4 years
7.0%
10+ years
6.0%


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