Principal Scientist Jobs in Waltham, MA
A Principal Scientist in the chemistry industry is responsible for conducting complex research, developing new procedures, and overseeing a team of scientists to ensure all projects are completed to a high standard. They typically perform experimental tests and analyses, interpreting and presenting results, and preparing research reports and scientific papers. Their work is instrumental in contributing to the development of new products, technologies, or intellectual property. They often work closely with other departments such as Regulatory Affairs, Quality Control, and Manufacturing to ensure all scientific operations meet the necessary standards and regulations.
Important skills for a Principal Scientist include leadership, excellent written and oral communication abilities, strong analytical skills, and the ability to work well in teams. They should have a thorough understanding of various scientific techniques and principles, and be adept at problem-solving. The minimum requirement for this position is typically a PhD in Chemistry or a related field, with substantial experience in the industry. Certifications that can add value include Certified Professional Chemist (CPC) or Certified Clinical Research Professional (CCRP). A person might work as a Research Scientist, Senior Scientist, or Project Leader before moving into the role of a Principal Scientist.
Associate Principal Scientist, PharmaR&D
- Boston, MA (10 miles from Waltham, MA)
- 1 day ago
- Boston, MA (10 miles from Waltham, MA)
- 1 day ago
Human Disease, Genetics/Genomics, Molecular Biology, or Immunology Comfort in a client-facing role Proficient in R or Python Strong understanding of the molecular nature of human disease Expert in delivering...
Senior Principal Scientist, Development DMPK
- Cambridge, MA (6 miles from Waltham, MA)
- 1 day ago
- Cambridge, MA (6 miles from Waltham, MA)
- 1 day ago
Job Requisition: Senior Principal Scientist, Development DMPK Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job....
Principal Scientist (Director) - Regulatory Affairs-CMC
- Boston, MA (10 miles from Waltham, MA)
- 2 days ago
- Boston, MA (10 miles from Waltham, MA)
- 2 days ago
**Director, Combination Product Regulatory CMC - (R5)** This Principal Scientist position is equivalent to a Director position....
Associate Principal Scientist, Bioinformatics, Immuno-Oncology Analytics
- Boston, MA (10 miles from Waltham, MA)
- 2 days ago
- Boston, MA (10 miles from Waltham, MA)
- 2 days ago
The Translational Genome Analytics group within the Data, AI & Genome Sciences Department is recruiting an Associate Principal Scientist to join our data science team....
Principal Scientist, Genetic Epidemiology & Biostatistics
- Cambridge, MA (6 miles from Waltham, MA)
- 2 days ago
- Cambridge, MA (6 miles from Waltham, MA)
- 2 days ago
Lead with hypothesis-driven thinking and demonstrate an ability to put questions in a translational/clinical context. Strong desire to perform individual contributor work in a collaborative...
Principal Scientist, Process Development Engineering, Media Development
- Boston, MA (10 miles from Waltham, MA)
- 3 days ago
- Boston, MA (10 miles from Waltham, MA)
- 3 days ago
Job Description General Summary: Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people living with serious diseases, with a...
Chromatography Principal Scientist
- Cambridge, MA (6 miles from Waltham, MA)
- 3 days ago
- Cambridge, MA (6 miles from Waltham, MA)
- 3 days ago
A PhD in Analytical Chemistry is preferred....
Principal Scientist/Lab Head - Oncology Biotherapeutics
- Cambridge, MA (6 miles from Waltham, MA)
- 4 days ago
- Cambridge, MA (6 miles from Waltham, MA)
- 4 days ago
Biology...
- Cambridge, MA (6 miles from Waltham, MA)
- 4 days ago
- Cambridge, MA (6 miles from Waltham, MA)
- 4 days ago
As a Principal Scientist, you will be expected to be able to use your knowledge of virology and molecular biology to independently design and execute experiments with guidance from the lab head and...
Principal Scientist, Machine Learning (Protein Design)
- Boston, MA (10 miles from Waltham, MA)
- 5 days ago
- Boston, MA (10 miles from Waltham, MA)
- 5 days ago
Principal Scientist, Machine Learning (Protein Design) Flagship Pioneering, Inc. Boston, MA Full Time Published on 06/08/2025...
Principal Scientist I, Computational Pathology, Precision Medicine Pathology
- Waltham, MA
- 5 days ago
- Waltham, MA
- 5 days ago
. + Familiarity with cell and molecular biology concepts relevant to immunology, cancer immunotherapy, or oncology, or a strong willingness to learn about these areas....
Principal Scientist, Chemistry
- Boston, MA (10 miles from Waltham, MA)
- 5 days ago
- Boston, MA (10 miles from Waltham, MA)
- 5 days ago
Seaport Therapeutics is a clinical-stage biopharmaceutical company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. The Company has a proven...
Associate Principal Scientist/Associate Director , Regulatory Affairs - Compliance
- Boston, MA (10 miles from Waltham, MA)
- 6 days ago
- Boston, MA (10 miles from Waltham, MA)
- 6 days ago
This position will be part of the Device Quality & Regulatory Team within Global Regulatory Affairs and Clinical Safety (GRACS). The primary responsibility for this position is to ensure...
Principal Scientist, Computational Neurotranscriptomics
- Cambridge, MA (6 miles from Waltham, MA)
- 6 days ago
- Cambridge, MA (6 miles from Waltham, MA)
- 6 days ago
The Principal Scientist will collaborate closely with a cross-functional team, working to develop generative AI approaches that leverage human gene expression information....
Principal Scientist, In Vivo Tumor Model Oncology Drug Discovery
- Cambridge, MA (6 miles from Waltham, MA)
- 8 days ago
- Cambridge, MA (6 miles from Waltham, MA)
- 8 days ago
The Oncology Intracellular Targeted Cancer Therapeutics Unit has an opening for an In Vivo Principal Scientist at its Cambridge, MA site....
Demographic Data for Waltham, MA
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Salary for Principal Scientist Jobs in Waltham, MA
Required or preferred licenses and certifications for Principal Scientist positions.
Highest Education Level
Principal Scientists in Waltham, MA offer the following education backgroundQualifications / Skill Sets
The following top skills are often required or desired to land a Principal Scientist position
- Affirmative Action
- Implementation
- ISO 13485
- Method Development
- Liquid Chromatography
- Analytical Chemistry
- ChemDraw
- Purification
- High-Performance Liquid Chromatography
- Liquid Chromatography Mass Spectrometry
- Chromatography
- Cell-Based Assays
- Gas Chromatography and Mass Spectrometry
- Assay Development
- Stability Testing
- Computational Chemistry
- Biomarkers
- Mass Spectrometry
- Chemical Characterization
- Method Validation
- Peptide Synthesis
- Drug Discovery
- Medicinal Chemistry
- Thermogravimetric Analysis
- Organic Chemistry
- Cancer Biology
- Lab Safety
- Immunoassays
- Flow Cytometry
- Biochemistry
- Bioinformatics
- Immunology
- Drug Development
- Experimental Design
- Good Laboratory Practice
- Molecular Biology
- Microbiology
- Laboratory Management
- Validation
- Biology
- Research and Development
- Process Development
- Hazardous Materials
- FDA Regulations
- Modeling
- Standard Operating Procedures
- Diagnostic
- Product Development
- Engineering
- Quality Control
- Troubleshooting
- Investigation
- Written Communication
- Presentation
- Mentoring
- Data Analysis
- Quality Assurance
- Collaboration
- Documentation
- Bachelor's Degree
- Reporting
- Regulations
- Project Management
- Problem Solving
- Research Skills
- Microsoft Excel
- Staff Supervision
- Organization
- Scheduling
- Leadership
- Communication Skills
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