Research Associate III - Stanley Center

  • The Broad Institute, Inc.
  • Cambridge, Massachusetts
  • Full Time
Research Associate III - Stanley Center

General information

Location

Cambridge, MA

Ref #

42695

Job Family

Research

Workplace

On-Site

Date published

25-Jul-2025

Time Type

Full time

Description & Requirements

The Broad Institute of MIT & Harvard is looking for an outstanding Research Associate II to join the experimentalist team in the Center for Human Brain Variation. The mission of the project is to address an unmet need in cell census research: to understand the cell-type-specific mechanisms and larger tissue-level biological principles that generate meaningful variation in brain biology among people.

We are seeking a highly motivated, collaborative Research Associate to support this important effort in close collaboration with other project scientists. The Research Associate should be able to conduct bench experiments with minimal supervision and will have opportunities to present at lab meetings and contribute to writing experimental protocols.

RESPONSIBILITIES

Contribute to experimental workflows for profiling the molecular contents and biological states of thousands of individual cells in brain tissue, contributing to all aspects including planning experiments, creating DNA-barcoding reagents; extracting nuclei from human brain tissue; preparing molecular libraries; and high-throughput sequencing

Optimize and execute molecular-biological reactions such as PCR, DNA extractions from human brain tissue, and next generation sequencing (NGS) library preparation

Maintain meticulous records and document all experiments in the lab notebook

Attend and contribute to team meetings

Contribute to generation and optimization of experimental protocols

QUALIFICATIONS

Bachelor's degree in biology, neuroscience, chemistry or a related field with 2+ years of related experience, or Master's degree with at least 1 year of related experience

Experience generating single-cell RNAseq, ATACseq, and multiome data preferred but not required.

Ability to critically read and discuss scientific research publications.

Strong ability to work both independently and collaboratively.

Excellent written and verbal communication skills.

Ability to thrive in a fast-paced rapidly changing environment.

Must be comfortable and able to work onsite five days per week.
Job ID: 487391211
Originally Posted on: 7/30/2025

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